Nature Search

Specificity of the Stereochemical Relationship Between Ribonucleic Acid-Triplets and Amino-Acids

M. G. E. WELTON
S. R. PELC
Research26 Feb 1966
Nature

Volume: 209, P: 870-872
Responses of a Fern Apex to Gibberellic Acid, Kinetin and α-Naphthaleneacetic Acid

C. W. WARDLAW
G. C. MITRA
Research08 Feb 1958
Nature

Volume: 181, P: 400-401
Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f

Smells are detected in the nose by odorant molecules binding to a specific G protein-coupled receptor on the cell surface. Here, authors have determined the atomic structure of a receptor bound to an odorant molecule that showing how the odorant binds and activates the receptor.

Anastasiia Gusach
Yang Lee
Christopher G. Tate
ResearchOpen Access30 Aug 2024
Nature Communications

Volume: 15, P: 1-12
Identification of nanomolar adenosine A_2A receptor ligands using reinforcement learning and structure-based drug design

Here the authors combine a deep generative model with structure-based drug design and prospectively validate functionally active, nanomolar, A_2A adenosine receptor ligands and solve their crystal structures to close the Artificial Intelligence Structure-Based Drug Design loop.

Morgan Thomas
Pierre G. Matricon
Chris de Graaf
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-14
Solution of Eigenvalue Problems

R. G. COOKE
Research05 Apr 1958
Nature

Volume: 181, P: 978-979
Allosteric modulation and biased signalling at free fatty acid receptor 2

Structural, pharmacological and computational studies reveal how different classes of positive allosteric modulators bind to distinct allosteric sites and use noncanonical mechanisms to activate the free-fatty acid receptor FFA2.

Xuan Zhang
Abdul-Akim Guseinov
Cheng Zhang
Research18 Jun 2025
Nature

Volume: 643, P: 1428-1438
Stereochemical Relationship Between Coding Triplets and Amino-Acids

S. R. PELC
M. G. E. WELTON
Research26 Feb 1966
Nature

Volume: 209, P: 868-870
Structural insights into lipid chain-length selectivity and allosteric regulation of FFA2

The authors present structures of FFA2 bound to TUG-1375/4-CMTB or GLPG0974, revealing how the receptor selects lipid chain lengths and is allosterically regulated by synthetic ligands.

Mai Kugawa
Kouki Kawakami
Hideaki E. Kato
ResearchOpen Access26 Mar 2025
Nature Communications

Volume: 16, P: 1-16
Effect of Gibberellic Acid on Length and Number of Epidermal Cells in Petioles of Strawberry

C. G. GUTTRIDGE
P. A. THOMPSON
Research17 Jan 1959
Nature

Volume: 183, P: 197-198
A love letter to Black feminist physicists

Jessica Esquivel
Books & Arts11 May 2021
Nature Physics

Volume: 17, P: 548
Metabolism of Aflatoxin in Sheep: Excretion of the ‘Milk Toxin’

R. ALLCROFT
H. ROGERS
P. E. BEST
Research08 Jan 1966
Nature

Volume: 209, P: 154-155
Structure of the adenosine A_2A receptor bound to an engineered G protein

An engineered G protein is used to bind to and stabilize the active conformation of the adenosine A_2A receptor, enabling the acquisition of an X-ray crystal structure of this GPCR in an active state.

Byron Carpenter
Rony Nehmé
Christopher G. Tate
Research27 Jul 2016
Nature

Volume: 536, P: 104-107
Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors

B. J. Bongers
M. Gorostiola González
G. J. P. van Westen
ResearchOpen Access13 Dec 2022
Scientific Reports

Volume: 12, P: 1-15
The Artificial Production of Mesons

G. P. S. OCCHIALINI
C. F. POWELL
Research10 Apr 1948
Nature

Volume: 161, P: 551-552
Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor

Different phosphorylation patterns created by GRK2 and GRK5 on the C-terminal tail of ACKR3 lead to distinct structural arrangements and dynamics of G-protein-coupled receptor–arrestin complexes, potentially explaining diverse cellular outcomes.

Qiuyan Chen
Christopher T. Schafer
John J. G. Tesmer
Research21 May 2025
Nature

Volume: 643, P: 280-287
The role of endogenous nerve growth factor in human diabetic neuropathy

P. Anand
G. Terenghi
D.V. Sinicropi
Research01 Jun 1996
Nature Medicine

Volume: 2, P: 703-707
A molecular cell atlas of mouse lemur, an emerging model primate

Together with a companion paper, the generation of a transcriptomic atlas for the mouse lemur and analyses of example cell types establish this animal as a molecularly tractable primate model organism.

Antoine de Morree
Iwijn De Vlaminck
Mark A. Krasnow
ResearchOpen Access30 Jul 2025
Nature

Volume: 644, P: 173-184
Air pollution increases Aphis fabae pest potential

G. P. Dohmen
S. McNeill
J. N. B. Bell
Research05 Jan 1984
Nature

Volume: 307, P: 52-53
The oxytocin signaling complex reveals a molecular switch for cation dependence

The cryo-EM structure and functional analyses of oxytocin bound to its receptor reveal a Mg²⁺ coordination complex in the binding pocket and find that the identity of a single residue determines whether a vasopressin/oxytocin family receptor requires Mg²⁺ as a cofactor.

Justin G. Meyerowitz
Michael J. Robertson
Georgios Skiniotis
Research03 Mar 2022
Nature Structural & Molecular Biology

Volume: 29, P: 274-281
Mouse lemur cell atlas informs primate genes, physiology and disease

Together with an accompanying paper presenting a transcriptomic atlas of the mouse lemur, interrogation of the atlas provides a rich body of data to support the use of the organism as a model for primate biology and health.

Camille Ezran
Shixuan Liu
Mark A. Krasnow
ResearchOpen Access30 Jul 2025
Nature

Volume: 644, P: 185-196
Possible Wind Transport of Coffee Leaf Rust across the Atlantic Ocean

J. BOWDEN
P. H. GREGORY
C. G. JOHNSON
Research12 Feb 1971
Nature

Volume: 229, P: 500-501
Structure of the adenosine-bound human adenosine A₁ receptor–G_i complex

The cryo-electron microscopy structure of the human adenosine A₁ receptor in complex with adenosine and heterotrimeric G_i2 protein provides molecular insights into receptor and G-protein selectivity.

Christopher J. Draper-Joyce
Maryam Khoshouei
Arthur Christopoulos
Research20 Jun 2018
Nature

Volume: 558, P: 559-563
Structure of the junction between communicating cells

P. N. T. Unwin
G. Zampighi
Research07 Feb 1980
Nature

Volume: 283, P: 545-549
Early pregnancy factor is immunosuppressive

F. P. NOONAN
W. J. HALLIDAY
G. J. A. CLUNIE
Research01 Apr 1979
Nature

Volume: 278, P: 649-651
Molecular signatures of G-protein-coupled receptors

A systematic investigation of high-resolution G-protein-coupled receptor (GPCR) structures uncovers a conserved inter-helical network of non-covalent contacts that defines the GPCR fold, and provides insights into the molecular determinants of different GPCR conformations.

A. J. Venkatakrishnan
Xavier Deupi
M. Madan Babu
Reviews13 Feb 2013
Nature

Volume: 494, P: 185-194
Similarity of the crystal and solution structure of yeast tRNA^Phe

G. T. Robillard
C. E. Tarr
H. J. C. Berendsen
Research01 Jul 1976
Nature

Volume: 262, P: 363-369
The moving emission features in SS433 require a dynamical interpretation

James Liebert
J. R. P. Angel
W. P. Blair
Research01 May 1980
Nature

Volume: 279, P: 384-387
Isolation, Identification and Synthesis of a specific-behaviour-inducing Brain Peptide

G. UNGAR
D. M. DESIDERIO
W. PARR
Research28 Jul 1972
Nature

Volume: 238, P: 198-202
Three-dimensional structure of yeast phenylalanine transfer RNA at 3. 0Å resolution

F. L. Suddath
G. J. Quigley
Alexander Rich
Research01 Mar 1974
Nature

Volume: 248, P: 20-24
Induction of cell–cell channel formation by mRNA

G. Dahl
R. Azarnia
R. Werner
Research19 Feb 1981
Nature

Volume: 289, P: 683-685
Evidence for inhibition of platelet activation in blood by a drug effect on erythrocytes

G. V. R. BORN
D. BERGQUIST
K.-E. ARFORS
Research22 Jan 1976
Nature

Volume: 259, P: 233-235
Structure of a β₁-adrenergic G-protein-coupled receptor

Tony Warne
Maria J. Serrano-Vega
Gebhard F. X. Schertler
Research01 Jul 2008
Nature

Volume: 454, P: 486-491
Evolution of the mammalian G protein α subunit multigene family

Thomas M. Wilkie
Debra J. Gilbert
Neal G. Copeland
Research01 May 1992
Nature Genetics

Volume: 1, P: 85-91
Tissue plasminogen activator (tPA) increase neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

Yanming F. Wang
Stella E. Tsirka
Stuart A. Lipton
Research01 Feb 1998
Nature Medicine

Volume: 4, P: 228-231
Caledonian Magmatism in North Wales

J. E. THOMAS
M. H. DODSON
G. FERRARA
Research26 Feb 1966
Nature

Volume: 209, P: 866-868
Ultraviolet spectrum of quasi–stellar object 3C273

Arthur F. Davidsen
George F. Hartig
William G. Fastie
Research15 Sept 1977
Nature

Volume: 269, P: 203-206
The Iron Dextran Complex

C. R. RICKETTS
J. S. G. COX
G. F. MOSS
Research16 Oct 1965
Nature

Volume: 208, P: 237-239
Citizen Science in Disaster and Conflict Resilience

Keith G Tidball
Marianne Krasny
ResearchOpen Access09 Nov 2010
Nature Precedings

P: 1
Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor

This study explores apelin receptor’s role in cardiovascular function, identifying residues critical for binding through genetic variants, AlphaFold2 modelling and base editing in cardiomyocytes. Co-crystallization with biased agonist CMF-019 shows a unique binding mode versus endogenous peptides.

Thomas L. Williams
Grégory Verdon
Anthony P. Davenport
ResearchOpen Access27 Dec 2024
Nature Communications

Volume: 15, P: 1-19
Biosynthesis of Insulin Chains A and B

A. S. KONIKOVA
S. A. MORENKOVA
M. G. KRITZMAN
Research05 Jun 1965
Nature

Volume: 206, P: 1005-1007
Manganese Nodules, Topography and Thickness of Quaternary Sediments in the Central Pacific

T. C. MOORE JUN.
G. R. HEATH
Research03 Dec 1966
Nature

Volume: 212, P: 983-985
An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism

GPR61 is an orphan GPCR of interest for treatment of appetite disorders, such as obesity and cachexia. Here, the authors report structures of GPR61 in its active and inactive states, including with a G protein-competitive small molecule inverse agonist.

Joshua A. Lees
João M. Dias
Seungil Han
ResearchOpen Access23 Sept 2023
Nature Communications

Volume: 14, P: 1-12
Genetic and Developmental Studies of a Quantitative Character

S. G. SPICKETT
Research31 Aug 1963
Nature

Volume: 199, P: 870-873
Epidermolytic palmoplantar keratoderma cosegregates with a keratin 9 mutation in a pedigree with breast and ovarian cancer

D. Torchard
C. Blanchet-Bardon
J. Feunteun
Research01 Jan 1994
Nature Genetics

Volume: 6, P: 106-110
Structures of benzo(a)pyrene–nucleic acid adducts formed in human and bovine bronchial explants

A. M. JEFFREY
I. B. WEINSTEIN
C. HARRIS
Research01 Sept 1977
Nature

Volume: 269, P: 348-350
Changes in Vat Dye Systems

G. S. EGERTON
F. GALIL
Research17 May 1958
Nature

Volume: 181, P: 1399-1400
Photochemical Stability of Dyes in the Solid State

G. S. EGERTON
A. G. ROACH
Research14 Dec 1957
Nature

Volume: 180, P: 1349-1350
Metabolism of dl-Ornithine-2-¹⁴C in Normal and Potassium-deficient Barley

R. G. COLEMAN
M. P. HEGARTV
Research16 Feb 1957
Nature

Volume: 179, P: 376-377
Kinetic Isotope Effect in the Bromination of Dimethylaniline

P. G. FARRELL
S. F. MASON
Research24 Jan 1959
Nature

Volume: 183, P: 250-251
Structure of the class D GPCR Ste2 dimer coupled to two G proteins

A cryo-electron microscopy structure of the yeast pheromone receptor Ste2, a class D G-protein-coupled receptor, in its active state reveals that Ste2 is a homodimer that couples to two G proteins.

Vaithish Velazhahan
Ning Ma
Christopher G. Tate
Research02 Dec 2020
Nature

Volume: 589, P: 148-153

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