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National identity predicts public health support during a global pandemic

Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported greater engagement in public health behaviours and support for public health policies in the context of the pandemic.

Jay J. Van Bavel
Aleksandra Cichocka
Paulo S. Boggio
ResearchOpen Access26 Jan 2022
Nature Communications

Volume: 13, P: 1-14
Evaluation of FluSight influenza forecasting in the 2021–22 and 2022–23 seasons with a new target laboratory-confirmed influenza hospitalizations

This manuscript evaluates forecasts of laboratory-confirmed influenza hospital admissions, a new target for influenza forecasting in the United States. Across two influenza seasons, the FluSight ensemble is robust compared to submitted models.

Sarabeth M. Mathis
Alexander E. Webber
Rebecca K. Borchering
ResearchOpen Access26 Jul 2024
Nature Communications

Volume: 15, P: 1-13
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer

The PI(3,4)P₂ 4-phosphatase, INPP4B, functions as a tumour suppressor in triple negative breast cancer. Here, the authors show that INPP4B enhances proliferation and growth of PIK3CA-mutant ER⁺ breast cancers by promoting PI3Kα-dependent late endosome formation and trafficking that leads to the activation of Wnt/β-catenin signalling.

Samuel J. Rodgers
Lisa M. Ooms
Christina A. Mitchell
ResearchOpen Access25 May 2021
Nature Communications

Volume: 12, P: 1-19
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer

Advanced pancreatic cancer is associated with tissue wasting; however, the timing of tissue loss prior to diagnosis and the potential utility of such loss for earlier pancreatic cancer detection are not well understood. Here the authors show that skeletal muscle loss can be detected on CT imaging 1–2 years before a clinical diagnosis of pancreatic cancer.

Ana Babic
Michael H. Rosenthal
Brian M. Wolpin
ResearchOpen Access18 Jul 2023
Nature Communications

Volume: 14, P: 1-9
Large spin–orbit torque in bismuthate-based heterostructures

A spin–orbit torque efficiency of around 2.7 can be achieved in heterostructures based on the bismuthate BaPb_1−xBi_xO₃, which can be used to drive magnetization switching at current densities of 4 × 10⁵ A cm⁻².

Anthony L. Edgeton
Isaac A. Harris
Chang-Beom Eom
Research05 Dec 2023
Nature Electronics

Volume: 6, P: 973-980
Adeno-associated virus 2 infection in children with non-A–E hepatitis

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Antonia Ho
Richard Orton
Emma C. Thomson
Research30 Mar 2023
Nature

Volume: 617, P: 555-563
Oncogenic effects of ECM remodeling in obesity and breast cancer

Mackenzie L. Hawes
Marcus A. Moody
Elizabeth C. Martin
ReviewsOpen Access22 Aug 2025
Oncogene

Volume: 44, P: 3409-3421
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Controlling spin current polarization through non-collinear antiferromagnetism

In the typical spin-hall effect, spin-current, charge current, and spin polarisation are all mutually perpendicular, a feature enforced by symmetry. Here, using an anti-ferromagnet with a triangular spin structure, the authors demonstrate a spin-hall effect without a perpendicular spin alignment.

T. Nan
C. X. Quintela
C. B. Eom
ResearchOpen Access16 Sept 2020
Nature Communications

Volume: 11, P: 1-7
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

William Evans and colleagues find that the proinflammatory genes CASP1 and NLRP3 are expressed at higher levels in primary acute lymphoblastic leukemia cells that are resistant than in those that are sensitive to glucocorticoid treatment. They find that CASP1 mediates glucocorticoid resistance through cleavage of the glucocorticoid receptor.

Steven W Paugh
Erik J Bonten
William E Evans
Research04 May 2015
Nature Genetics

Volume: 47, P: 607-614
Meeting sustainable development goals via robotics and autonomous systems

A horizon scan was used to explore possible impacts of robotics and automated systems on achieving the UN Sustainable Development Goals. Positive effects are likely. Iterative regulatory processes and continued dialogue could help avoid environmental damages and increases in inequality.

Solène Guenat
Phil Purnell
Martin Dallimer
ResearchOpen Access21 Jun 2022
Nature Communications

Volume: 13, P: 1-10
Thermoresponsive gels containing gold nanoparticles as smart antibacterial and wound healing agents

Mona G. Arafa
Reham F. El-Kased
M. M. Elmazar
ResearchOpen Access12 Sept 2018
Scientific Reports

Volume: 8, P: 1-16
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Author Correction: National identity predicts public health support during a global pandemic

Jay J. Van Bavel
Aleksandra Cichocka
Paulo S. Boggio
Amendments and CorrectionsOpen Access06 Apr 2022
Nature Communications

Volume: 13, P: 1-2
Homocysteine and methylmalonic acid levels in pregnant Nepali women. Should cobalamin supplementation be considered?

GT Bondevik
J Schneede
G Kvåle
Research03 Oct 2001
European Journal of Clinical Nutrition

Volume: 55, P: 856-864
Conservative management of double penetrating ocular injuries

Mustafa Iqbal
David G Charteris
G l S Mackintosh
Correspondence01 Mar 2000
Eye

Volume: 14, P: 249-251
The United States COVID-19 Forecast Hub dataset

Estee Y. Cramer
Yuxin Huang
Nicholas G. Reich
ResearchOpen Access01 Aug 2022
Scientific Data

Volume: 9, P: 1-15
Social and moral psychology of COVID-19 across 69 countries

Flavio Azevedo
Tomislav Pavlović
Waldir M. Sampaio
ResearchOpen Access11 May 2023
Scientific Data

Volume: 10, P: 1-26

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