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Showing 51–100 of 529 results

Advanced filters: Author: G. Moloney Clear advanced filters

A homologue of Drosophila tissue polarity gene frizzled is expressed in migrating myofibroblasts in the infarcted rat heart

W. Matthijs Blankesteijn
Yvonne P.G. Essers-Janssen
Jos F.M. Smits
Research01 May 1997
Nature Medicine

Volume: 3, P: 541-544
Functional association of cyclophilin A with HIV-1 virions

Markus Thali
Anatoly Bukovsky
Heinrich G. Göttlinger
Research24 Nov 1994
Nature

Volume: 372, P: 363-365
Germline NPM1 mutations lead to altered rRNA 2′-O-methylation and cause dyskeratosis congenita

NPM1 regulates ribosomal RNA 2′-O-methylation by binding to small nucleolar RNAs, thereby modulating translation. NPM1 mutations lead to altered 2′-O-methylation and impaired ribosomal function, resulting in bone marrow failure and leukemia susceptibility.

Daphna Nachmani
Anne H. Bothmer
Pier Paolo Pandolfi
Research30 Sept 2019
Nature Genetics

Volume: 51, P: 1518-1529
Reduction in SIV replication in rhesus macaques infused with autologous lymphocytes engineered with antiviral genes

Robert E. Donahue
Bruce A. Bunnell
Richard A. Morgan
Research01 Feb 1998
Nature Medicine

Volume: 4, P: 181-186
Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells

Janne L. Simonsen
Cecilia Rosada
Moustapha Kassem
Research01 Jun 2002
Nature Biotechnology

Volume: 20, P: 592-596
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture

Manfred Schwab
Harold E. Varmus
J. Michael Bishop
Research11 Jul 1985
Nature

Volume: 316, P: 160-162
The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination

Host microRNAs control both cellular processes and viral protein translation. Mandelboim et al. demonstrate synergism between host and viral microRNAs in downregulating the activatory ligand MICB, which facilitates immune evasion.

Daphna Nachmani
Dikla Lankry
Ofer Mandelboim
Research08 Aug 2010
Nature Immunology

Volume: 11, P: 806-813
Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury

Zhi-yong Yang
Henricus J. Duckers
Gary J. Nabel
Research01 Aug 2000
Nature Medicine

Volume: 6, P: 886-889
Nonspecific and specific immuno-suppression in tumour-bearing mice by soluble immune complexes

R. M. GORCZYNSKI
D. G. KILBURN
J. B. SMITH
Research13 Mar 1975
Nature

Volume: 254, P: 141-143
Mapping of an endogenous retroviral sequence to human chromosome 18

Stephen J. O'Brien
Tom I. Bonner
William G. Nash
Research05 May 1983
Nature

Volume: 303, P: 74-77
[Book Reviews]

G. H. S. BUSHNELL
Books & Arts03 May 1952
Nature

Volume: 169, P: 725
Activation of K cells in mice with transplanted tumours differing in immunogenicity and metastasizing capacity

A Mantovani
N Polentarutti
F Spreafico
Research01 Oct 1977
British Journal of Cancer

Volume: 36, P: 453-460
onc sequences (v-fes) of Snyder–Theilen feline sarcoma virus are derived from noncontiguous regions of a cat cellular gene (c-fes)

G. Franchini
J. Even
F. Wong-Staal
Research12 Mar 1981
Nature

Volume: 290, P: 154-157
Crystal structure of dimeric HIV-1 capsid protein

Cory Momany
Ladislau C. Kovari
Michael G. Rossmann
Research01 Sept 1996
Nature Structural Biology

Volume: 3, P: 763-770
Marine litter keeps increasing

Peter G. Ryan
Coleen L. Moloney
Research07 Jan 1993
Nature

Volume: 361, P: 23
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels

Sanshool, the compound responsible for the tingling sensations experienced when consuming Szechuan peppercorns, excites sensory neurons through a unique mechanism, the inhibition of two-pore potassium channels.

Diana M Bautista
Yaron M Sigal
David Julius
Research22 Jun 2008
Nature Neuroscience

Volume: 11, P: 772-779
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers

We evaluate the effects in humans of interleukin-15 co-expression on glypican-3 (GPC3) chimeric antigen receptor (CAR) T cells and demonstrate that IL-15 increases the expansion, intratumoural survival and antitumour activity of GPC3 (expressed in a group of solid cancers) CAR T cells.

David Steffin
Nisha Ghatwai
Andras Heczey
Research27 Nov 2024
Nature

Volume: 637, P: 940-946
Leucine zipper-based immunomagnetic purification of CAR T cells displaying multiple receptors

A cell-sorting method leveraging leucine zippers allows for the generation of T cells displaying multiple chimaeric antigen receptors as well as receptors converting inhibitory signals into stimulatory signals.

Scott E. James
Sophia Chen
Marcel R. M. van den Brink
Research23 Dec 2024
Nature Biomedical Engineering

Volume: 8, P: 1592-1614
Multiple mRNA species with distinct 3′ termini are transcribed from the β₂-microglobulin gene

Jane R. Parnes
Randy R. Robinson
J. G. Seidman
Research31 Mar 1983
Nature

Volume: 302, P: 449-452
Subclonal mutation selection in mouse lymphomagenesis identifies known cancer loci and suggests novel candidates

Evidence implicating cancer drivers can be sparse when limited to clonal events. Here, the authors present a retrovirus driven in vivo lymphomagenesis time course including hundreds of thousands of subclonal mutations and demonstrate the utility of these in mapping the selective forces affecting cancer gene loci, including negatively selected mutations.

Philip Webster
Joanna C. Dawes
Anthony G. Uren
ResearchOpen Access09 Jul 2018
Nature Communications

Volume: 9, P: 1-14
Experimental metastasis correlates with cyclic AMP accumulation in B16 melanoma clones

J. R. Sheppard
Thomas P. Koestler
George Poste
Research05 Apr 1984
Nature

Volume: 308, P: 544-547
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis

MYCN-amplified neuroblastoma remains an aggressive childhood cancer with its core regulatory circuits less understood. Here, the authors identify that the transcriptional corepressor Runx1t1 is indispensable for MYCN-driven neuroblastoma tumorigenesis.

Jayne E. Murray
Emanuele Valli
Murray D. Norris
ResearchOpen Access11 Jul 2024
Nature Communications

Volume: 15, P: 1-21
Inhibitory effect of YC8 leukaemia cell line on in vitro lymphocyte reactivity

G Biasi
D Collavo
L Chieco-Bianchi
Research01 May 1977
British Journal of Cancer

Volume: 35, P: 528-536
Optimizing 5’UTRs for mRNA-delivered gene editing using deep learning

mRNA therapeutics are revolutionizing the pharmaceutical industry. In this study, the authors characterize 5’UTR-regulated translation in cell types relevant for mRNA therapies and with fully random 5’UTRs, and show that 5’UTRs optimized via deep learning support high performance on mRNA-encoded gene editors.

Sebastian Castillo-Hair
Stephen Fedak
Georg Seelig
ResearchOpen Access20 Jun 2024
Nature Communications

Volume: 15, P: 1-15
Dynamic encounters with red blood cells trigger splenic marginal zone B cell retention and function

Cyster and colleagues show that CD97–CD55 interactions, which trigger Gα₁₃–ARHGEF–Rho cytoskeletal signaling, are needed for proper MZ B cell positioning/retention in the spleen and for optimal antibody responses to T cell-independent antigens.

Dan Liu
Benjamin Y. Winer
Jason G. Cyster
ResearchOpen Access04 Dec 2023
Nature Immunology

Volume: 25, P: 142-154
Detection of Circulating Hepatoma D23 Antigen and Immune Complexes in Tumour Bearer Serum

R W Baldwin
J G Bowen
M R Price
Research01 Jul 1973
British Journal of Cancer

Volume: 28, P: 16-24
Crystallographic Data for the Hexon of Adenovirus Type 5

W. M. MACINTYRE
H. G. PEREIRA
W. C. RUSSELL
Research21 Jun 1969
Nature

Volume: 222, P: 1165-1166
Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7

The interferon response is a critical component of the innate immune response. Here the authors implicate MNDA in the regulation of type I interferon responses to pathogen infection.

Lili Gu
David Casserly
Andrew G. Bowie
ResearchOpen Access10 Jan 2022
Nature Communications

Volume: 13, P: 1-14
Plasma Concentration and Excretion of Calcium-47, Strontium-85, Barium-133 and Radium-223 following Successive Intravenous Doses to a Healthy Man

G. E. HARRISON
T. E. F. CARR
J. RUNDO
Research29 Jan 1966
Nature

Volume: 209, P: 526-527
A Lactic Dehydrogenase Elevating Agent in Association with Human Neoplasms

C. G. CRISPENS JUN.
Research21 Sept 1963
Nature

Volume: 199, P: 1202-1203
World-wide Source of Leaf-derived Freezing Nuclei

R. C. SCHNELL
G. VALI
Research23 Nov 1973
Nature

Volume: 246, P: 212-213
Continuous Irradiation with Tritiated Water of Mammalian Cells in a Monolayer

A. H. W. NIAS
L. G. LAJTHA
Research09 May 1964
Nature

Volume: 202, P: 613-614
Variegation of retroviral vector gene expression in myeloid cells

L Zentilin
G Qin
M Giacca
Research08 Feb 2000
Gene Therapy

Volume: 7, P: 153-166
Corrigendum: Major shear zones and autochthonous Dalradian in the north-east Scottish Caledonides

W. A. Ashcroft
B. C. Kneller
M. Munro
Research13 Feb 1986
Nature

Volume: 319, P: 606
Quick Preparation of Corolla Chromosomes from Flower Buds

G. HASKELL
E. B. PATERSON
Research08 Aug 1964
Nature

Volume: 203, P: 673-674
Nuclear Sheets in Epithelial and Connective Tissue Cells

FRANCO MOLLO
MARIA G. CANESE
ALDO STRAMIGNONI
Research01 Mar 1969
Nature

Volume: 221, P: 869-870
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

William S. Hayward
Benjamin G. Neel
Susan M. Astrin
Research09 Apr 1981
Nature

Volume: 290, P: 475-480
A male steroid controls female sexual behaviour in the malaria mosquito

The discovery of a male-specific sex hormone in the mosquito <em>Anopheles gambiae</em> may allow new strategies for the control of this notorious disease vector.

Duo Peng
Evdoxia G. Kakani
Flaminia Catteruccia
ResearchOpen Access06 Jul 2022
Nature

Volume: 608, P: 93-97
Chemistry of hot springs on the Mid-Atlantic Ridge

A. C. Campbell
M. R. Palmer
J. A. Karson
Research06 Oct 1988
Nature

Volume: 335, P: 514-519
FMEV vectors: both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells

M Hildinger
H-G Eckert
C Baum
Research13 Nov 1998
Gene Therapy

Volume: 5, P: 1575-1579
Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state

There is much interest in generating motor neurons from embryonic stem cells because they may be useful for the study of neurodegenerative disease. Pataniet al. show that in the absence of retinoic acid, neurons with features of medial motor columnar neurons can be generated from human embryonic stem cells.

R. Patani
A. J. Hollins
S. Chandran
ResearchOpen Access01 Mar 2011
Nature Communications

Volume: 2, P: 1-10
Branched Cells in the Epidermis of the Sheep

A. G. LYNE
H. B. CHASE
Research26 Mar 1966
Nature

Volume: 209, P: 1357-1358
A method for classification of 5′ termini of retroviruses

William A. Haseltine
Dennis G. Kleid
Research01 Jun 1978
Nature

Volume: 273, P: 358-364
Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results

In updated results from a phase 1 trial of GD2-specific CAR-NKT cells in patients with neuroblastoma, no dose-limiting toxicities were observed across multiple dose levels; the maximum tolerated dose was not reached; and there was evidence of anti-tumor activity.

Andras Heczey
Xin Xu
Leonid S. Metelitsa
Research15 May 2023
Nature Medicine

Volume: 29, P: 1379-1388
Formation of sapropels in the Tyro Basin (reply)

S. R. TROELSTRA
G. T. KLAVER
D. JONGSMA
Research21 Jun 1984
Nature

Volume: 309, P: 728
Herpesviruses assimilate kinesin to produce motorized viral particles

Herpes simplex virus type I and pseudorabies virus assimilate kinesin from host epithelial cells and repurpose the motor to traffic to the nuclei of neurons in the peripheral nervous system.

Caitlin E. Pegg
Sofia V. Zaichick
Gregory A. Smith
Research17 Nov 2021
Nature

Volume: 599, P: 662-666
Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis

LATS1 is reported to regulate the transition of luminal-basal-like cell plasticity in breast cancer. Here the authors report that LATS1 limits the progression of luminal breast cancer by associating with NCOR1 nuclear corepressor to repress ERα-downregulated genes in luminal cells.

Yael Aylon
Noa Furth
Moshe Oren
ResearchOpen Access28 Nov 2022
Nature Communications

Volume: 13, P: 1-20
Relationship between receptor and mammary tumour virus production after stimulation by glucocorticoid

G. Shyamala
C. Dickson
Research01 Jul 1976
Nature

Volume: 262, P: 107-112
Telomerized human microvasculature is functional in vivo

Jiwei Yang
Usha Nagavarapu
G. Scott Herron
Research01 Mar 2001
Nature Biotechnology

Volume: 19, P: 219-224
Different β-subunits determine G-protein interaction with transmembrane receptors

C. Kleuss
H. Scherübl
B. Wittig
Research30 Jul 1992
Nature

Volume: 358, P: 424-426

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