Certain RIFINs from Plasmodium falciparum can bind to both inhibitory (KIR2DL1) and activating (KIR2DS1) immune receptors on natural killer cells, demonstrating the potential role of activating killer immunoglobulin-like receptors in targeting pathogens and controlling malaria infection.
- Akihito Sakoguchi
- Samuel G. Chamberlain
- Shiroh Iwanaga