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Advanced filters: Author: Gabe Haller Clear advanced filters

Massively parallel single-nucleotide mutagenesis using reversibly terminated inosine

The incorporation of reversibly terminated deoxyinosine triphosphates during linear amplification allows the incorporation of one mutation per molecule and the generation of a systematic allelic series.

Gabe Haller
David Alvarado
Christina A Gurnett
Research03 Oct 2016
Nature Methods

Volume: 13, P: 923-924
A missense variant in SLC39A8 is associated with severe idiopathic scoliosis

The majority of scoliosis is considered idiopathic with onset in adolescence (AIS) and has a genetic contribution. Here, the authors perform an exome wide association study of data from 457 severe AIS cases and 987 controls, and find a missense variant in SLC39A8 is associated with AIS.

Gabe Haller
Kevin McCall
Christina A. Gurnett
ResearchOpen Access09 Oct 2018
Nature Communications

Volume: 9, P: 1-7
Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy

Brooke Sadler
Gabe Haller
Alison Goate
ResearchOpen Access28 Mar 2014
Scientific Reports

Volume: 4, P: 1-8