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Advanced filters: Author: Gabriel Gershenfeld Clear advanced filters

  • An analysis of more than 50 collaborations shows the secrets of success, write Joel Cutcher-Gershenfeld and colleagues from the Stakeholder Alignment Collaborative.

    • Joel Cutcher-Gershenfeld
    • Karen S. Baker
    • Ilya Zaslavsky
    Comments & Opinion
    Nature
    Volume: 543, P: 615-617

  • If the activity of genetically specified neurons is silenced in a temporally precise fashion, the roles of different cell classes in neural processes can be studied. Members of the class of light-driven outward proton pumps are now shown to mediate powerful, safe, multiple-colour silencing of neural activity. The gene archaerhodopsin-3 (Arch) enables near 100% silencing of neurons in the awake brain when virally expressed in the mouse cortex and illuminated with yellow light.

    • Brian Y. Chow
    • Xue Han
    • Edward S. Boyden
    Research
    Nature
    Volume: 463, P: 98-102