Nature Search

Myocardial infarction accelerates atherosclerosis

Myocardial infarction accelerates atherosclerosis through activation of the sympathetic nervous system, and the consequent release of haematopoietic stem and progenitor cells.

Partha Dutta
Gabriel Courties
Matthias Nahrendorf
Research27 Jun 2012
Nature

Volume: 487, P: 325-329
Proteomic analysis of cardiorespiratory fitness for prediction of mortality and multisystem disease risks

A proteomic risk score for cardiorespiratory fitness, comprising as few as 21 proteins, is dynamic with exercise training and helps predict the risk of mortality and a range of cardiovascular, metabolic and neurological conditions.

Andrew S. Perry
Eric Farber-Eger
Ravi V. Shah
ResearchOpen Access04 Jun 2024
Nature Medicine

Volume: 30, P: 1711-1721
Regulating T helper cell immunity through antigen responsiveness and calcium entry

Gabriel Bikah
Rebecca R. Pogue-Caley
Michael G. McHeyzer-Williams
Research01 Nov 2000
Nature Immunology

Volume: 1, P: 402-412
Massively parallel de novo protein design for targeted therapeutics

A massively parallel computational and experimental approach for de novo designing and screening small hyperstable proteins targeting influenza haemagglutinin and botulinum neurotoxin B identifies new therapeutic candidates more robust than traditional antibody therapies.

Aaron Chevalier
Daniel-Adriano Silva
David Baker
Research27 Sept 2017
Nature

Volume: 550, P: 74-79
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Most studies of the genetics of the metabolome have been done in individuals of European descent. Here, the authors integrate genomics and metabolomics in Black individuals, highlighting the value of whole genome sequencing in diverse populations and linking circulating metabolites to human disease.

Usman A. Tahir
Daniel H. Katz
Robert E. Gerszten
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-16
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B

Crystal structures of human APOBEC3A and a chimera of APOBEC3B and APOBEC3A bound to ssDNA reveal an unanticipated ‘U-shaped’ binding mode and provide insight into target selectivity.

Ke Shi
Michael A Carpenter
Hideki Aihara
Research19 Dec 2016
Nature Structural & Molecular Biology

Volume: 24, P: 131-139
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia

Lasry and Nadorp et al. use single-cell RNA sequencing and CITE sequencing to reveal inflammatory gene expression in a subset of pediatric and adult patients with acute myeloid leukemia that associates with changes in the immune microenvironment and generate an inflammatory score with prognostic potential.

Audrey Lasry
Bettina Nadorp
Iannis Aifantis
Research29 Dec 2022
Nature Cancer

Volume: 4, P: 27-42
Identification of neurobehavioural symptom groups based on shared brain mechanisms

Ing et al. develop a method of establishing direct relationships between psychiatric symptoms and neuroimaging measures of brain structure and function and use it to stratify adolescent psychopathology on the basis of underlying biology. They replicate their results in independent clinical samples.

Alex Ing
Philipp G. Sämann
Gunter Schumann
Research07 Oct 2019
Nature Human Behaviour

Volume: 3, P: 1306-1318
Author Correction: An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia

Audrey Lasry
Bettina Nadorp
Iannis Aifantis
Amendments and Corrections19 Jan 2023
Nature Cancer

Volume: 4, P: 149
Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents

Some adolescents seek novelty, but it is unknown whether the brain circuits underlying this behaviour can be used to predict later, problematic behaviour. Here, authors show that diminished ventral striatal and prefrontal activity in response to anticipated rewards at age 14 in these individuals predicts problematic drug use at age 16.

Christian Büchel
Jan Peters
Veronika Ziesch
ResearchOpen Access21 Feb 2017
Nature Communications

Volume: 8, P: 1-11
MRI and PET/CT in the assessment of lymph node metastases in head and neck cancer

Paul Zwittag
Christian Asel
Nikolaus Poier-Fabian
ResearchOpen Access07 Nov 2023
Scientific Reports

Volume: 13, P: 1-10
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex

Hansen et al. compile and share an atlas of neurotransmitter receptor/transporter densities in the human cortex and show that receptor achitecture reflects brain structure, function, dynamics, cognitive specialization and disease vulnerability.

Justine Y. Hansen
Golia Shafiei
Bratislav Misic
ResearchOpen Access27 Oct 2022
Nature Neuroscience

Volume: 25, P: 1569-1581
Distinct systemic cytokine networks in symptomatic and asymptomatic carotid stenosis

Ricarda D. Stauss
Gerrit M. Grosse
Claudia Schrimpf
ResearchOpen Access15 Dec 2020
Scientific Reports

Volume: 10, P: 1-13
MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3⁺ regulatory T cells

Charis E. Teh
Alissa K. Robbins
Daniel H. D. Gray
Research01 Jul 2020
Cell Death & Differentiation

Volume: 27, P: 3374-3385
Disturbance and mosquito diversity in the lowland tropical rainforest of central Panama

Jose R. Loaiza
Larissa C. Dutari
Montira Pongsiri
ResearchOpen Access03 Aug 2017
Scientific Reports

Volume: 7, P: 1-13
Differential predictors for alcohol use in adolescents as a function of familial risk

Mira Tschorn
Robert C. Lorenz
Amir Tahmasebi
ResearchOpen Access04 Mar 2021
Translational Psychiatry

Volume: 11, P: 1-11
The IMAGEN study: a decade of imaging genetics in adolescents

Lea Mascarell Maričić
Henrik Walter
Amir Tahmasebi
ReviewsOpen Access29 Jun 2020
Molecular Psychiatry

Volume: 25, P: 2648-2671

Search

Myocardial infarction accelerates atherosclerosis

Proteomic analysis of cardiorespiratory fitness for prediction of mortality and multisystem disease risks

Regulating T helper cell immunity through antigen responsiveness and calcium entry

Massively parallel de novo protein design for targeted therapeutics

Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia

Identification of neurobehavioural symptom groups based on shared brain mechanisms

Author Correction: An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia

Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents

MRI and PET/CT in the assessment of lymph node metastases in head and neck cancer

Mapping neurotransmitter systems to the structural and functional organization of the human neocortex

Distinct systemic cytokine networks in symptomatic and asymptomatic carotid stenosis

MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3⁺ regulatory T cells

Disturbance and mosquito diversity in the lowland tropical rainforest of central Panama

Differential predictors for alcohol use in adolescents as a function of familial risk

The IMAGEN study: a decade of imaging genetics in adolescents

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