It is promising but elusive to use covalent organic frameworks (COFs)-based chromatic sensors for chemical tomography – or the 3D spatial mapping of chemical details within living systems. Here, the authors report a COF-silk fibroin microneedle interface capable of 3D mapping of the chemical environment at standoff distances from the plant, enabling in-vivo chemical tomography.
- Song Wang
- Yangyang Han
- Michael S. Strano
