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Showing 1–4 of 4 results
Advanced filters: Author: Gaby Sroczynski Clear advanced filters
  • A new study has reported the long-term effectiveness and cost-effectiveness of the direct-acting antivirals telaprevir and boceprevir for the treatment of chronic hepatitis C. These findings have the potential to be used to guide clinical and reimbursement decisions for treating populations with a high prevalence of HCV infection.

    • Gaby Sroczynski
    • Uwe Siebert
    News & Views
    Nature Reviews Gastroenterology & Hepatology
    Volume: 10, P: 572-574
  • Risk-adapted approaches to breast cancer prevention and screening could potentially be more effective than universal approaches, which have important limitations. In this Consensus Statement, representatives of the European Collaborative on Personalized Early Detection and Prevention of Breast Cancer (ENVISION) discuss the current state of breast cancer risk prediction, risk-stratified prevention and early detection strategies, and their implementation. They also present the ENVISION recommendations on priorities for future research in each of these areas with the aim of stimulating and guiding risk-adapted breast cancer prevention and screening programmes.

    • Nora Pashayan
    • Antonis C. Antoniou
    • Martin Widschwendter
    ReviewsOpen Access
    Nature Reviews Clinical Oncology
    Volume: 17, P: 687-705
  • The development of cancer involves several epigenomic alterations, and the presence of certain alterations before the development of cancer is associated with cancer risk. In this Review, the authors describe the potential of epigenomics-based assays to predict an individual's risk of cancer, including discussions of technical, practical and societal issues regarding the implementation of such assays.

    • Martin Widschwendter
    • Allison Jones
    • Nora Pashayan
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 15, P: 292-309