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Advanced filters: Author: Gaoang Ren Clear advanced filters

  • The transcription factor retinoid X receptor-alpha (RXRα) can also form homotetramers. Here the authors show that the anti-cancer agent K-80003 selectively inhibits the nongenomic action of N-terminally-cleaved RXRα in tumour cells by stabilizing its tetramerization but not that of full-length RXRα.

    • Liqun Chen
    • Alexander E. Aleshin
    • Xiao-kun Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14