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Showing 1–2 of 2 results
Advanced filters: Author: Garry L. Coles Clear advanced filters

  • The combination of anti-GD2 and CD47 blockade mediates robust anti-tumor activity in mouse models of neuroblastoma, osteosarcoma and small-cell lung cancer by reorienting macrophage activity toward tumor cell phagocytosis.

    • Johanna Theruvath
    • Marie Menard
    • Robbie G. Majzner
    Research
    Nature Medicine
    Volume: 28, P: 333-344

  • Notch signaling is known to control neuroendocrine fate in the lungs. Shue and colleagues further identify the REST and YAP transcriptional regulators as key components of the Notch signaling pathway in the control of the neuroendocrine cell fate in lung development, lung injury response, and small-cell lung cancer.

    • Yan Ting Shue
    • Alexandros P. Drainas
    • Julien Sage
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18