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Showing 151–200 of 334 results

Advanced filters: Author: Gavin Young Clear advanced filters

2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease

A panel of experts from the World Heart Federation provide a revised set of guidelines for the echocardiographic detection of rheumatic heart disease (RHD) in patients living in RHD-endemic regions. The guidelines provide updated screening and confirmatory criteria, as well as a new stage-based classification of RHD based on risk of disease progression, which will improve the diagnosis and subsequent management of patients with RHD.

Joselyn Rwebembera
James Marangou
Bo Reményi
Reviews02 Nov 2023
Nature Reviews Cardiology

Volume: 21, P: 250-263
Look who's talking too: graduates developing skills through communication

Ability to effectively communicate one's research is a vital and highly transferable skill. It is therefore important that young scientists have opportunities to present their doctoral research to large general audiences.

Eleni M. Tomazou
Gareth T. Powell
Comments & Opinion07 Aug 2007
Nature Reviews Genetics

Volume: 8, P: 724-726
VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

Vascular endothelial growth factor is implicated in blood vessel development. In zebrafish, Hayashi et al. find that blood vessel development is dependent on the suppression of vascular endothelial growth factor by the phosphatase VE-PTP, which is recruited by activation of the angiopoietin receptor Tie2.

Makoto Hayashi
Arindam Majumdar
Lena Claesson-Welsh
ResearchOpen Access09 Apr 2013
Nature Communications

Volume: 4, P: 1-15
Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state

S Prakash
S Agrawal
A Agrawal
Research23 Apr 2014
Mucosal Immunology

Volume: 7, P: 1386-1394
Bipolar androgen therapy plus olaparib in men with metastatic castration-resistant prostate cancer

Michael T. Schweizer
Roman Gulati
Evan Y. Yu
Research23 Dec 2022
Prostate Cancer and Prostatic Diseases

Volume: 26, P: 194-200
World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease—an evidence-based guideline

Echocardiographic screening for rheumatic heart disease (RHD) over the past 5 years has revealed a higher RHD disease burden than previously imagined and, globally, at least 15 million people are estimated to be affected by this disease. In this article, an international advisory group of experts in RHD screening and echocardiographic manifestations of RHD present the 2012 World Heart Federation criteria for echocardiographic diagnosis of RHD.

Bo Reményi
Nigel Wilson
Jonathan Carapetis
Reviews28 Feb 2012
Nature Reviews Cardiology

Volume: 9, P: 297-309
Genomic reconstruction of the SARS-CoV-2 epidemic in England

A study of the evolution of the SARS-CoV-2 virus in England between September 2020 and June 2021 finds that interventions capable of containing previous variants were insufficient to stop the more transmissible Alpha and Delta variants.

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
ResearchOpen Access14 Oct 2021
Nature

Volume: 600, P: 506-511
The Prevalence of Behavioural Symptoms and Psychiatric Disorders in Hadza Children

Dennis Ougrin
Emma Woodhouse
Ioannis Bakolis
ResearchOpen Access12 Dec 2023
Scientific Reports

Volume: 13, P: 1-9
Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae

Transcriptomic analyses of acute phase whole blood from a large cohort of patients with COVID-19 identify molecular determinants of post-infection long-term sequelae.

Ryan C. Thompson
Nicole W. Simons
Noam D. Beckmann
ResearchOpen Access08 Dec 2022
Nature Medicine

Volume: 29, P: 236-246
Chemical and sensory properties of South Tyrol red wines from disease-resistant and Vitis vinifera cultivars

Gavin Duley
Adriana Teresa Ceci
Emanuele Boselli
ResearchOpen Access09 May 2025
npj Science of Food

Volume: 9, P: 1-17
Assessing the impact of population stratification on genetic association studies

Matthew L Freedman
David Reich
David Altshuler
Research28 Mar 2004
Nature Genetics

Volume: 36, P: 388-393
Biomimetic synthesis of the IDO inhibitors exiguamine A and B

Matthew Volgraf
Jean-Philip Lumb
Dirk Trauner
Research01 Aug 2008
Nature Chemical Biology

Volume: 4, P: 535-537
Cohesin relocation from sites of chromosomal loading to places of convergent transcription

Armelle Lengronne
Yuki Katou
Frank Uhlmann
Research30 Jun 2004
Nature

Volume: 430, P: 573-578
Ability of swept source OCT to detect retinal changes in patients with bipolar disorder

Vicente Polo
Maria Satue
Elena Garcia-Martin
Research31 Oct 2018
Eye

Volume: 33, P: 549-556
A clinical study of patients with novel CDHR1 genotypes associated with late-onset macular dystrophy

Rola Ba-Abbad
Anthony G. Robson
Andrew R. Webster
ResearchOpen Access17 Jul 2020
Eye

Volume: 35, P: 1482-1489
Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Bernardo Rodriguez-Martin
Eva G. Alvarez
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1080
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers

Yuan Yuan
Young Seok Ju
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1078
Bone morphogenetic protein 4 (BMP4) loss-of-function variant associated with autosomal dominant Stickler syndrome and renal dysplasia

Thomas R. W. Nixon
Allan Richards
Martin P. Snead
ResearchOpen Access19 Dec 2018
European Journal of Human Genetics

Volume: 27, P: 369-377
Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

Yulia Rubanova
Ruian Shi
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring

A new approach for whole-genome sequencing of plasma circulating tumor DNA allows for dynamic monitoring of disease burden and ultra-sensitive detection of minimal residual disease.

Asaf Zviran
Rafael C. Schulman
Dan A. Landau
Research01 Jun 2020
Nature Medicine

Volume: 26, P: 1114-1124
Author Correction: Inferring structural variant cancer cell fraction

Marek Cmero
Ke Yuan
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: The evolutionary history of 2,658 cancers

Moritz Gerstung
Clemency Jolly
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E42
A new kind of scientist

Climate researchers must begin to bridge disciplinary divides — and institutions must begin to reward them for it.

Gavin Schmidt
Elisabeth Moyer
Comments & Opinion31 Jul 2008
Nature Climate Change

Volume: 1, P: 102-103
Capturing a rhodopsin receptor signalling cascade across a native membrane

The rhodopsin signalling cascade, initiated by light, is captured using mass spectrometry of a native membrane.

Siyun Chen
Tamar Getter
Carol V. Robinson
ResearchOpen Access06 Apr 2022
Nature

Volume: 604, P: 384-390
Estimating the proportion of variation in susceptibility to multiple sclerosis captured by common SNPs

Corey T. Watson
Giulio Disanto
Sreeram V. Ramagopalan
ResearchOpen Access25 Oct 2012
Scientific Reports

Volume: 2, P: 1-4
Mitochondrial DNA deletion and sarcopenia

Vallabh O Shah
John Scariano
Dominic S C Raj
Research01 Mar 2009
Genetics in Medicine

Volume: 11, P: 147-152
Kinetics of slow release of nitrogen fertiliser from multi-layered nanofibrous structures

Leila Javazmi
Anthony Young
Tobias Low
ResearchOpen Access01 Mar 2021
Scientific Reports

Volume: 11, P: 1-8
Insights into hominid evolution from the gorilla genome sequence

The genome of a western lowland gorilla has been sequenced and analysed, completing the genome sequences of all great ape genera, and providing evidence for parallel accelerated evolution in chimpanzee, gorilla and human lineages at a number of loci.

Aylwyn Scally
Julien Y. Dutheil
Richard Durbin
ResearchOpen Access07 Mar 2012
Nature

Volume: 483, P: 169-175
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch

Notch signals are crucial for organization of angiogenic sprouting cells into the leading ‘tip’ and trailing ‘stalk’ cells. Here the authors show that endothelial neuropilin-1 quantitatively inhibits TGF-β/BMP signalling, explaining how Notch-mediated regulation of neuropilin-1 specifies endothelial tip and stalk cells.

Irene Maria Aspalter
Emma Gordon
Holger Gerhardt
ResearchOpen Access17 Jun 2015
Nature Communications

Volume: 6, P: 1-13
Investigation of slow release of urea from biodegradable single- and double-layered hollow nanofibre yarns

Leila Javazmi
Tobias Low
Anthony Young
ResearchOpen Access12 Nov 2020
Scientific Reports

Volume: 10, P: 1-9
Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

Glaucoma is the most common cause of irreversible blindness worldwide. Here, the authors carry out a large meta-analysis of genetic data from individuals of European and Asian ancestry and identify 10 new loci associated with vertical cup-disc ratio, a key factor in the clinical assessment of patients with glaucoma.

Henriët. Springelkamp
René Höhn
Christopher J. Hammond
ResearchOpen Access22 Sept 2014
Nature Communications

Volume: 5, P: 1-7
Behaviour of the Pleistocene marsupial lion deduced from claw marks in a southwestern Australian cave

Samuel D. Arman
Gavin J. Prideaux
ResearchOpen Access15 Feb 2016
Scientific Reports

Volume: 6, P: 1-8
Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis and neuromyelitis optica spectrum disorder — recommendations from ECTRIMS and the EBMT

Autologous haematopoietic stem cell transplantation (AHSCT) is a treatment option for some forms of multiple sclerosis (MS), but uncertainties remain about its implementation in clinical practice and treatment protocols need to be optimized. This Consensus Statement provides guidance and recommendations for the use of AHSCT in MS and neuromyelitis optica spectrum disorders.

Paolo A. Muraro
Alice Mariottini
Helene Zephir
Reviews15 Jan 2025
Nature Reviews Neurology

Volume: 21, P: 140-158
Single-cell multiomic analyses sheds light on mitochondrial mutational selection

Single large-scale mitochondrial DNA deletions cause a spectrum of disease with differing severities and tissue expressivity. Quantification of single-cell deletion levels with multi-modal cellular readouts provides insights into hematopoietic cell fate and disease manifestation.

Sarah J. Pickett
Gavin Hudson
Laura C. Greaves
News & Views29 Jun 2023
Nature Genetics

Volume: 55, P: 1083-1085
Resourceful imprinting

A child's genes are not all equal: in some cases, the copy from either the mother or the father is turned off. This affects the child's ability to acquire resources in the womb, after birth, and perhaps throughout life.

Miguel Constância
Gavin Kelsey
Wolf Reik
Comments & Opinion03 Nov 2004
Nature

Volume: 432, P: 53-57
Growth Arrest and DNA-Damage-Inducible, Beta (GADD45b)-Mediated DNA Demethylation in Major Psychosis

David P Gavin
Rajiv P Sharma
Alessandro Guidotti
Research02 Nov 2011
Neuropsychopharmacology

Volume: 37, P: 531-542
Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells

Laura Poisa-Beiro
Judith Thoma
Anthony D. Ho
ResearchOpen Access14 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

The molecular nature of large-cell neuroendocrine lung carcinomas (LCNEC) has remained unclear. Here, the authors show LCNECs represent a distinct transcriptional subgroup among lung cancers and comprise two molecular subgroups, type I (TP53 and STK11/KEAP1 alterations) and type II (TP53 and RB1 inactivation).

Julie George
Vonn Walter
Roman K. Thomas
ResearchOpen Access13 Mar 2018
Nature Communications

Volume: 9, P: 1-13
Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway

Urolithins are microbial metabolites derived from food polyphenols. Here, Singh et al. show that urolithin A and a synthetic analogue enhance gut barrier function via Nrf2-dependent pathways and mitigate inflammation and colitis in mice, highlighting a potential application for inflammatory bowel diseases.

Rajbir Singh
Sandeep Chandrashekharappa
Venkatakrishna R. Jala
ResearchOpen Access09 Jan 2019
Nature Communications

Volume: 10, P: 1-18
Correction: Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians

Ching-Yu Cheng
Kenji Yamashiro
Chiea Chuen Khor
Amendments and Corrections30 Mar 2015
Nature Communications

Volume: 6, P: 1
Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

Benedict D. Michael
Cordelia Dunai
David K. Menon
Amendments and CorrectionsOpen Access04 Apr 2024
Nature Communications

Volume: 15, P: 1
Proteomic association with age-dependent sex differences in Wisconsin Card Sorting Test performance in healthy Thai subjects

Chen Chen
Bupachad Khanthiyong
Sutisa Nudmamud-Thanoi
ResearchOpen Access19 Nov 2023
Scientific Reports

Volume: 13, P: 1-15
An outcome-driven threshold for pulse pressure amplification

Qi-Fang Huang
De-Wei An
Matias Pécora
ResearchOpen Access22 Jul 2024
Hypertension Research

Volume: 47, P: 2478-2488
Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Kadir C. Akdemir
Victoria T. Le
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1079
Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer

Lina Sieverling
Chen Hong
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Integrative pathway enrichment analysis of multivariate omics data

Marta Paczkowska
Jonathan Barenboim
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

Yiqun Zhang
Fengju Chen
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Esther Rheinbay
Morten Muhlig Nielsen
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E40
Author Correction: Patterns of somatic structural variation in human cancer genomes

Yilong Li
Nicola D. Roberts
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E38
Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Isidro Cortés-Ciriano
Jake June-Koo Lee
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1076

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