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Advanced filters: Author: Genevieve Holzapfel Clear advanced filters

  • HIV binding is mediated via CD4 and chemokine co-receptors, but this does not explain the preferential infection of central memory CD4+ T cells. Here the authors show HIV targets L-selectin, induces shedding from the infected cell, and inhibition of L-selectin reduces HIV infection and release.

    • Joseph Kononchik
    • Joanna Ireland
    • Peter Sun
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15