Anti-PIT1 hypophysitis is a form of paraneoplastic autoimmune hypophysitis. The condition is attributable to the ectopic expression of pituitary-specific positive transcription factor 1 (PIT1) in tumour tissues, which leads to autoimmunity against PIT1-positive anterior pituitary cells. In the past few years, it has been reported that anti-PIT1 hypophysitis can occur as an immune checkpoint inhibitor-related hypophysitis.
- Shin Urai
- Genzo Iguchi
- Yutaka Takahashi
