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Showing 1–3 of 3 results
Advanced filters: Author: Georg Alexander Häcker Clear advanced filters

  • Taxonomical complexity has muddled the classification of clinically relevant Enterobacter species. Authors carry out a genome-based study on clinical isolates to investigate colistin resistance and heteroresistance in Enterobacter.

    • Swapnil Prakash Doijad
    • Nicolas Gisch
    • Trinad Chakraborty
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • The anaphase-promoting complex/cyclosome (APC/C) is key to cell cycle regulation and is an E3 ubiquitin ligase. The overall shape of the substrate-free complex has previously been determined in various species. Budding yeast and human APC/Cs are now analyzed by EM structural and biochemical approaches to assess the substrate-binding site and elucidate the relative positioning of Doc1, a factor known to promote processive substrate ubiquitylation.

    • Bettina A Buschhorn
    • Georg Petzold
    • Jan-Michael Peters
    Research
    Nature Structural & Molecular Biology
    Volume: 18, P: 6-13