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Showing 1–5 of 5 results
Advanced filters: Author: George I. Hagstrom Clear advanced filters

  • Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease with a substantial burden worldwide. In this Consensus Statement, a global multidisciplinary group of experts develop consensus statements and recommendations addressing a broad range of topics on NAFLD to raise awareness and spur action.

    • Jeffrey V. Lazarus
    • Henry E. Mark
    • Ming-Hua Zheng
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 19, P: 60-78

  • FXR regulates the levels of ACE2 in tissues of the respiratory and gastrointestinal systems that are affected by COVID-19, and inhibiting FXR with ursodeoxycholic acid downregulates ACE2 and reduces susceptibility to SARS-CoV-2 infection.

    • Teresa Brevini
    • Mailis Maes
    • Fotios Sampaziotis
    ResearchOpen Access
    Nature
    Volume: 615, P: 134-142

  • Gonçalo Abecasis and colleagues report a large-scale meta-analysis of genome-wide association studies for age-related macular degeneration (AMD), including over 17,100 advanced cases and 60,000 controls. They identify seven loci newly associated with AMD and report pathway analysis that shows enrichment in the complement system and atherosclerosis signaling.

    • Lars G Fritsche
    • Wei Chen
    • Gonçalo R Abecasis
    Research
    Nature Genetics
    Volume: 45, P: 433-439