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Showing 1–3 of 3 results
Advanced filters: Author: George Spracklin Clear advanced filters

  • The authors find that silent chromatin is more diverse than just facultative and constitutive heterochromatin. These inactive types have distinct three-dimensional interaction characteristics that are transposable if the underlying chromatin state is altered.

    • George Spracklin
    • Nezar Abdennur
    • Job Dekker
    ResearchOpen Access
    Nature Structural & Molecular Biology
    Volume: 30, P: 38-51

  • Double-stranded RNA interference (RNAi) in Caenorhabditis elegans is heritable; here a genetic screen for factors required for RNAi inheritance identifies the nuclear-localized Argonaute gene hrde-1, which acts in the germ cells of progeny to promote multigenerational inheritance of silencing and, also, germline immortality.

    • Bethany A. Buckley
    • Kirk B. Burkhart
    • Scott Kennedy
    Research
    Nature
    Volume: 489, P: 447-451

  • ZNFX-1 and WAGO-4 localize to germ granules in early Caenorhabditis elegans embryogenesis and later separate to form independent liquid-like droplets, and the temporal and spatial ordering of these droplets may help cells to organize complex RNA processing pathways.

    • Gang Wan
    • Brandon D. Fields
    • Scott Kennedy
    Research
    Nature
    Volume: 557, P: 679-683