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Showing 1–12 of 12 results
Advanced filters: Author: Georgia Giannoukos Clear advanced filters

  • Hybrid selection RNA sequencing of Bacteroides fragilis from colonic lumen, mucus and epithelial tissue samples, typically enriched with host reads, revealed the spatial transcriptome of this commensal throughout the murine colon and allowed the identification of putative colonization factors.

    • Gregory P. Donaldson
    • Wen-Chi Chou
    • Sarkis K. Mazmanian
    Research
    Nature Microbiology
    Volume: 5, P: 746-756

  • Single-molecule-based sequencing technology is applied to generate genome-wide maps of chromatin modifications in mammalian cells. Histone marks can discriminate genes that are active, poised for activation, or stably repressed and therefore reflect cell state and developmental potential.

    • Tarjei S. Mikkelsen
    • Manching Ku
    • Bradley E. Bernstein
    Research
    Nature
    Volume: 448, P: 553-560

  • An international consortium reports the genomic sequence for ten Drosophila species, and compares them to two other previously published Drosophila species. These data are invaluable for drawing evolutionary conclusions across an entire phylogeny of species at once.

    • Andrew G. Clark
    • Michael B. Eisen
    • Iain MacCallum
    Research
    Nature
    Volume: 450, P: 203-218

  • The Human Microbiome Project Consortium has established a population-scale framework to study a variety of microbial communities that exist throughout the human body, enabling the generation of a range of quality-controlled data as well as community resources.

    • Barbara A. Methé
    • Karen E. Nelson
    • Owen White
    ResearchOpen Access
    Nature
    Volume: 486, P: 215-221

  • The Human Microbiome Project Consortium reports the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome.

    • Curtis Huttenhower
    • Dirk Gevers
    • Owen White
    ResearchOpen Access
    Nature
    Volume: 486, P: 207-214

  • The genome of the grey short-tailed opossum Monodelphis domestica has been sequenced and analyzed, giving a first peek at a marsupial's genetic code. Of particular interest are the genetics of the immune system, which has been studied as a model for humans, and of the X chromosome for historical reasons.

    • Tarjei S. Mikkelsen
    • Matthew J. Wakefield
    • Kerstin Lindblad-Toh
    Research
    Nature
    Volume: 447, P: 167-177