Access to the brain remains a challenge in surgical and drug treatment of neurological disorders, but therapeutic use of ultrasound offers a realistic alternative to overcome the challenges. In this Review, the authors provide an overview of how ultrasound can be used for neurosurgery to ablate pathological tissue, for drug delivery by opening the blood–brain barrier, and for neuromodulation.
- Gerhard Leinenga
- Christian Langton
- Jürgen Götz