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Showing 1–3 of 3 results
Advanced filters: Author: Gerhard Paar Clear advanced filters

  • Treatment of the chronic disease ulcerative colitis is impeded by systemic side effects of orally administered drugs. Here the authors develop a gel that uses the rectal temperature as a mechanism to trigger solidification for localized delivery of colitis therapeutics.

    • Marianna Carone
    • Marianne R. Spalinger
    • Simone Aleandri
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • When the Philae lander bounced on the surface of comet 67P/Churyumov–Gerasimenko, it exposed primitive icy-dust material within cometary boulders; the intrinsic strength and porosity of this material is reported.

    • Laurence O’Rourke
    • Philip Heinisch
    • Holger Sierks
    Research
    Nature
    Volume: 586, P: 697-701

  • Multinucleated giant cells (MGCs) are important in the pathogenesis of various diseases. Here, the authors demonstrate that extracellular presence of the amino acid arginine is required for MGC formation and metabolism, suggesting a translational impact for strategies utilizing systemic arginine depletion in MGC-mediated diseases.

    • Julia S. Brunner
    • Loan Vulliard
    • Gernot Schabbauer
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15