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Advanced filters: Author: Gherardo Mazziotti Clear advanced filters

  • In this Review, Gherardo Mazziotti and Andrea Giustina discuss the latest advances in our understanding of how glucocorticoids affect the secretion of growth hormone. The implications for diagnosis and treatment of growth hormone deficiency in patients with a lack or excess of glucocorticoids will also be outlined.

    • Gherardo Mazziotti
    • Andrea Giustina
    Reviews
    Nature Reviews Endocrinology
    Volume: 9, P: 265-276

  • The growth hormone (GH)–insulin-like growth factor 1 (IGF1) axis regulates bone remodelling and metabolism. This Review highlights the pathophysiological and clinical aspects of skeletal fragility associated with perturbations in the GH–IGF1 axis such as GH deficiency, anorexia nervosa, ageing and acromegaly.

    • Gherardo Mazziotti
    • Andrea G. Lania
    • Ernesto Canalis
    Reviews
    Nature Reviews Endocrinology
    Volume: 18, P: 353-365