Hydrogen sulfide is a gaseous transmitter that shares features with nitric oxide (a key gaseous transmitter in erectile function) and has been shown to be involved in vascular homeostasis. In this Perspectives, the authors present available evidence in support of a physiological role for hydrogen sulfide in penile homeostasis and propose that drugs that manipulate this molecule could be an alternative therapy for erectile dysfunction.
- Roberta d'Emmanuele di Villa Bianca
- Raffaella Sorrentino
- Giuseppe Cirino