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Showing 1–50 of 75 results

Advanced filters: Author: Go Fujimoto Clear advanced filters

Transforming jet flavour tagging at ATLAS

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

G. Aad
E. Aakvaag
L. Zwalinski
ResearchOpen Access14 Jan 2026
Nature Communications

Volume: 17, P: 1-22
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A single-cell multiomic immune cell atlas from 235 Japanese, including patients with COVID-19 and healthy individuals, linked with host genetics including germline and somatic mutation, plasma proteomics and metagenomics data reveals that immune cells are dynamically regulated in a cell state-dependent manner.

Ryuya Edahiro
Go Sato
Yukinori Okada
ResearchOpen Access28 Jul 2025
Nature Genetics

Volume: 57, P: 1905-1921
Targeting fibroblast derived thrombospondin 2 disrupts an immune-exclusionary environment at the tumor front in colorectal cancer

Desmoplastic stroma is a hallmark of aggressive colorectal cancer. Matrix cancer-associated fibroblasts derived THBS2 establishes a fibrotic, immune-exclusionary barrier that limits CD8⁺ T cell infiltration, while its inhibition restores CXCR3-mediated T cell recruitment and enhances response to immune checkpoint blockade.

Kosuke Iwane
Yuki Nakanishi
Hiroshi Seno
ResearchOpen Access23 Nov 2025
Nature Communications

Volume: 16, P: 1-20
Selective production of transgenic mice using green fluorescent protein as a marker

Tatsuyuki Takada
Keiko lida
Gozoh Tsujimoto
Research01 May 1997
Nature Biotechnology

Volume: 15, P: 458-461
The impact of landscape structure on pesticide exposure to honey bees

Pesticides must be evaluated for their exposure to honey bees across diverse landscapes. This study reveals that both agricultural lands and urban areas resulted in higher pesticide exposure of bees, whereas forests were considered pesticide mitigation areas.

Shumpei Hisamoto
Makihiko Ikegami
Yoshiko Sakamoto
ResearchOpen Access22 Oct 2024
Nature Communications

Volume: 15, P: 1-11
Distinct roles of monkey OFC-subcortical pathways in adaptive behavior

The OFC is at the core of value-based adaptive decision-making. Here, the authors demonstrate dissociable contributions of primate OFC-subcortical pathways to different behavioral strategies by combining chemogenetics with a model-fitting approach.

Kei Oyama
Kei Majima
Takafumi Minamimoto
ResearchOpen Access28 Aug 2024
Nature Communications

Volume: 15, P: 1-13
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

Hidewaki Nakagawa and colleagues report a comprehensive genome-wide mutational landscape of 300 liver cancers from Japanese individuals. They identify candidate driver mutations, including ones in noncoding regions, and structural mutations affecting the expression of nearby genes.

Akihiro Fujimoto
Mayuko Furuta
Hidewaki Nakagawa
Research11 Apr 2016
Nature Genetics

Volume: 48, P: 500-509
Structure of coagulation factors IX/X-binding protein, a heterodimer of C-type lectin domains

Coagulation factors IX/X-binding protein is an intertwined dimer with a central loop projecting into the adjoining subunit. Excluding this loop, each subunit has a fold similar to rat mannose-binding protein.

Hiroshi Mizuno
Zui Fujimoto
Takashi Morita
Correspondence01 Jun 1997
Nature Structural Biology

Volume: 4, P: 438-441
Integrated exome and RNA sequencing of dedifferentiated liposarcoma

Understanding the genomic features of dedifferentiated liposarcoma (DDLPS) is likely to uncover new options for management. Here, the authors reveal three prognostic groups, and highlight molecular markers associated with malignant transformation.

Makoto Hirata
Naofumi Asano
Koichi Matsuda
ResearchOpen Access12 Dec 2019
Nature Communications

Volume: 10, P: 1-12
A pristine record of outer Solar System materials from asteroid Ryugu’s returned sample

The sample taken from carbonaceous asteroid Ryugu and brought back to Earth by the Hayabusa2 spacecraft contains outer Solar System-derived materials uncontaminated by terrestrial processes. Even CI carbonaceous chondrites, despite their closeness to solar abundances, are not pristine.

Motoo Ito
Naotaka Tomioka
Yuichi Tsuda
ResearchOpen Access15 Aug 2022
Nature Astronomy

Volume: 6, P: 1163-1171
Impact of lean body mass index on short-term outcomes in patients with ischemic stroke: an observational cohort study

Go Hashimoto
Kuniyuki Nakamura
Takuya Kiyohara
ResearchOpen Access23 Dec 2025
Scientific Reports

Volume: 16, P: 1-10
Deficiency of a pyrroline-5-carboxylate reductase produces the yellowish green cocoon ‘Ryokuken’ of the silkworm, Bombyx mori

Chikara Hirayama
Keisuke Mase
Kimiko Yamamoto
Research23 Feb 2018
Heredity

Volume: 120, P: 422-436
Observation of quantum entanglement with top quarks at the ATLAS detector

Entanglement was observed in top–antitop quark events by the ATLAS experiment produced at the Large Hadron Collider at CERN using a proton–proton collision dataset with a centre-of-mass energy of √s = 13 TeV and an integrated luminosity of 140 fb⁻¹.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access18 Sept 2024
Nature

Volume: 633, P: 542-547
PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation

Processing the value of reward is thought to involve the rostromedial caudate (rmCD), but a causal demonstration is lacking in primates. Here the authors use chemogenetics and PET imaging to show that inactivation of rmCD leads to impairments in reward value judgments.

Yuji Nagai
Erika Kikuchi
Takafumi Minamimoto
ResearchOpen Access06 Dec 2016
Nature Communications

Volume: 7, P: 1-8
Connexin32 as a tumor suppressor gene in a metastatic renal cell carcinoma cell line

Eriko Fujimoto
Hiromi Sato
Tomohiro Yano
Research14 Mar 2005
Oncogene

Volume: 24, P: 3684-3690
Optimal degrees of freedom of the lower extremities for human walking and running

Shoma Kudo
Masahiro Fujimoto
Akinori Nagano
ResearchOpen Access27 Sept 2023
Scientific Reports

Volume: 13, P: 1-5
Diversification of endosymbiosis: replacements, co-speciation and promiscuity of bacteriocyte symbionts in weevils

Hirokazu Toju
Akifumi S Tanabe
Takema Fukatsu
Research28 Feb 2013
The ISME Journal

Volume: 7, P: 1378-1390
Freeze-Dried Platelet-Rich Plasma Accelerates Bone Union with Adequate Rigidity in Posterolateral Lumbar Fusion Surgery Model in Rats

Yasuhiro Shiga
Sumihisa Orita
Seiji Ohtori
ResearchOpen Access11 Nov 2016
Scientific Reports

Volume: 6, P: 1-10
Scintillating Organic–Inorganic Layered Perovskite-type Compounds and the Gamma-ray Detection Capabilities

Naoki Kawano
Masanori Koshimizu
Keisuke Asai
ResearchOpen Access07 Nov 2017
Scientific Reports

Volume: 7, P: 1-8
A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

Ten years after the discovery of the Higgs boson, the ATLAS experiment at CERN probes its kinematic properties with a significantly larger dataset from 2015–2018 and provides further insights on its interaction with other known particles.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access04 Jul 2022
Nature

Volume: 607, P: 52-59
Significance of secretory leukocyte peptidase inhibitor in pleural fluid for the diagnosis of benign asbestos pleural effusion

Takumi Kishimoto
Yoko Kojima
Nobukazu Fujimoto
ResearchOpen Access21 Jun 2021
Scientific Reports

Volume: 11, P: 1-9
Nanoengineering of cathode layers for solid oxide fuel cells to achieve superior power densities

High-performance cathode materials are crucial for the development of solid oxide fuel cells. Here, the authors present a nanoengineering approach to boost cathode performance in conventional anode-supported cells, demonstrating a viable route to attaining higher power output.

Katherine Develos-Bagarinao
Tomohiro Ishiyama
Katsuhiko Yamaji
ResearchOpen Access25 Jun 2021
Nature Communications

Volume: 12, P: 1-12
Publisher Correction: Integrated exome and RNA sequencing of dedifferentiated liposarcoma

Makoto Hirata
Naofumi Asano
Koichi Matsuda
Amendments and CorrectionsOpen Access19 Feb 2020
Nature Communications

Volume: 11, P: 1
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

Hidewaki Nakagawa and colleagues report the whole-genome sequencing of 27 hepatocellular carcinomas. They find that chromatin regulators were mutated in approximately 50% of tumors.

Akihiro Fujimoto
Yasushi Totoki
Hidewaki Nakagawa
Research27 May 2012
Nature Genetics

Volume: 44, P: 760-764
Radiocesium contamination of greenlings (Hexagrammos otakii) off the coast of Fukushima

Yuya Shigenobu
Ken Fujimoto
Tomowo Watanabe
ResearchOpen Access31 Oct 2014
Scientific Reports

Volume: 4, P: 1-6
Exploration of liver cancer genomes

Advances in sequencing technologies have enabled the examination of liver cancer genomes at high resolution. The authors of this Review discuss somatic mutations, structural alterations, HBV integration, RNA editing and retrotransposon changes associated with liver cancer. Potential therapeutic targets are also highlighted.

Tatsuhiro Shibata
Hiroyuki Aburatani
Reviews28 Jan 2014
Nature Reviews Gastroenterology & Hepatology

Volume: 11, P: 340-349
Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines

Izumi Miyake
Yuko Hakomori
Ryuichi Sakai
Research29 Aug 2002
Oncogene

Volume: 21, P: 5823-5834
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Deschloroclozapine (DCZ) is a broadly useful chemogenetic agonist for studies using nonhuman primates and mice. DCZ rapidly and reversibly activates DREADDs, and its binding can be visualized noninvasively by positron emission tomography.

Yuji Nagai
Naohisa Miyakawa
Takafumi Minamimoto
Research06 Jul 2020
Nature Neuroscience

Volume: 23, P: 1157-1167
Preliminary analysis of the Hayabusa2 samples returned from C-type asteroid Ryugu

The Hayabusa2 spacecraft returned 5.4 g of material from the asteroid Ryugu. A first analysis of the samples found an estimated density of 1,282 ± 231 kg m⁻³, considerably lower than even the most porous meteorites. Together with preliminary spectral analysis, these results indicate that Ryugu is similar to CI chondrites, but darker, more porous and more brittle.

Toru Yada
Masanao Abe
Yuichi Tsuda
ResearchOpen Access20 Dec 2021
Nature Astronomy

Volume: 6, P: 214-220
Coseismic fluid–rock interactions at high temperatures in the Chelungpu fault

Chemical and isotopic variations in crushed material along the Chelungpu fault in Taiwan are suggestive of interactions at high temperatures with coseismically generated aqueous fluids. High fluid pressures along the fault zone during the magnitude 7.6 Chi-Chi earthquake in 1999 could have reduced friction and fault strength.

Tsuyoshi Ishikawa
Masaharu Tanimizu
Sheng-Rong Song
Research14 Sept 2008
Nature Geoscience

Volume: 1, P: 679-683
Trends of Arbekacin-resistant MRSA Strains in Japanese Hospitals (1979 to 2000)

Naofumi Tsuchizaki
Keiko Ishino
Kunimoto Hotta
Research01 Apr 2006
The Journal of Antibiotics

Volume: 59, P: 229-233
Spatiotemporal and kinematic gait characteristics in older patients with type 2 diabetes mellitus with and without sarcopenia

Tomotaka Manabe
Wakako Tsuchida
Koji Murao
ResearchOpen Access27 May 2025
Scientific Reports

Volume: 15, P: 1-9
Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia

Kana Yamamoto
Toshihiko Kuriu
Takanobu Nakazawa
ResearchOpen Access25 Oct 2021
Translational Psychiatry

Volume: 11, P: 1-8
Combination of long-read and short-read sequencing provides comprehensive transcriptome and new insight for Chrysanthemum morifolium ray-floret colorization

Mitsuko Kishi-Kaboshi
Tsuyoshi Tanaka
Ryutaro Aida
ResearchOpen Access25 Oct 2022
Scientific Reports

Volume: 12, P: 1-15
Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification

Naohiro Okada
Masaki Fukunaga
Ryota Hashimoto
ResearchOpen Access04 Aug 2023
Molecular Psychiatry

Volume: 28, P: 5206-5216
Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals

Junya Matsumoto
Masaki Fukunaga
Ryota Hashimoto
ResearchOpen Access18 Aug 2023
Molecular Psychiatry

Volume: 28, P: 4915-4923
Prognostic significance of right subdiaphragmatic washing cytology in patients with endometrial cancer

Takanori Yokoyama
Shinichi Okame
Kazuhiro Takehara
ResearchOpen Access18 Jan 2025
Scientific Reports

Volume: 15, P: 1-10
Genome analysis of the kiwifruit canker pathogen Pseudomonas syringae pv. actinidiae biovar 5

Takashi Fujikawa
Hiroyuki Sawada
ResearchOpen Access19 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Combination treatment with a PI3K/Akt/mTOR pathway inhibitor overcomes resistance to anti-HER2 therapy in PIK3CA-mutant HER2-positive breast cancer cells

Yumi Fujimoto
Tomoko Yamamori Morita
Toru Mukohara
ResearchOpen Access10 Dec 2020
Scientific Reports

Volume: 10, P: 1-16
Gaze behaviors during free viewing revealed differences in visual salience processing across four major psychiatric disorders: a mega-analysis study of 1012 individuals

Kenichiro Miura
Masatoshi Yoshida
Ryota Hashimoto
ResearchOpen Access11 Oct 2024
Molecular Psychiatry

Volume: 30, P: 1594-1600
Lipidomic Signatures and Associated Transcriptomic Profiles of Clear Cell Renal Cell Carcinoma

Kosuke Saito
Eri Arai
Yoshiro Saito
ResearchOpen Access30 Jun 2016
Scientific Reports

Volume: 6, P: 1-12
Differences in fractional anisotropy between the patients with schizophrenia and healthy comparison subjects

Daisuke Koshiyama
Masaki Fukunaga
Ryota Hashimoto
Research14 Apr 2020
Molecular Psychiatry

Volume: 25, P: 697-698
Solar abundance ratios of the iron-peak elements in the Perseus cluster

High-resolution X-ray spectra show near-solar abundances of chromium, manganese and nickel with respect to iron in the Perseus cluster, suggesting that the progenitors of type Ia supernovae could be near- and sub-Chandrasekhar-mass white dwarfs.

Felix Aharonian
Hiroki Akamatsu
Abderahmen Zoghbi
Research01 Nov 2017
Nature

Volume: 551, P: 478-480
Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Kazunori Toyoda
Masatoshi Koga
Hiroaki Tanaka
ResearchOpen Access09 Jul 2024
Hypertension Research

Volume: 47, P: 2238-2249
Visual salience is affected in participants with schizophrenia during free-viewing

Masatoshi Yoshida
Kenichiro Miura
Ryota Hashimoto
ResearchOpen Access26 Feb 2024
Scientific Reports

Volume: 14, P: 1-12
White matter microstructural alterations across four major psychiatric disorders: mega-analysis study in 2937 individuals

Daisuke Koshiyama
Masaki Fukunaga
Ryota Hashimoto
ResearchOpen Access29 Nov 2019
Molecular Psychiatry

Volume: 25, P: 883-895
Efficacy and safety of losartan 100 mg/hydrochlorothiazide 12.5 mg in Japanese subjects with essential hypertension: two randomized, controlled trials

Hiromi Rakugi
Takuya Tsuchihashi
Kenji P Fujita
Research03 Jul 2014
Hypertension Research

Volume: 37, P: 1042-1049
Narcolepsy type I-associated DNA methylation and gene expression changes in the human leukocyte antigen region

Kugui Yoshida-Tanaka
Mihoko Shimada
Taku Miyagawa
ResearchOpen Access28 Jun 2023
Scientific Reports

Volume: 13, P: 1-12
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

G. Aad
B. Abbott
L. Zwalinski
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E5
Gene therapy with SOCS1 for gastric cancer induces G2/M arrest and has an antitumour effect on peritoneal carcinomatosis

Rie Natatsuka
Tsuyoshi Takahashi
Tetsuji Naka
ResearchOpen Access16 Jul 2015
British Journal of Cancer

Volume: 113, P: 433-442

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