Here the authors analyze the Alzheimer’s Disease Neuroimaging Initiative dataset using random forest machine learning methods and determine that Aβ and tau biomarkers are better predictors of early dementia status, while glucose hypometabolism is a better predictor of later dementia status. These results suggest the need for stage-oriented Alzheimer’s disease treatments.
- Tyler C. Hammond
- Xin Xing
- Ai-Ling Lin