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Showing 1–6 of 6 results
Advanced filters: Author: Gorka Alkorta-Aranburu Clear advanced filters

  • The genes EGLN1 and EPAS1 are candidates for high-altitude adaptations in Tibetan populations. Here, Jeong et al. demonstrate that the two genes show evidence of high-altitude ancestry in the Tibetan genome, suggesting the importance of population admixture for adaptation.

    • Choongwon Jeong
    • Gorka Alkorta-Aranburu
    • Anna Di Rienzo
    Research
    Nature Communications
    Volume: 5, P: 1-7

  • The microbiota of the intestinal tract is considered a large biofilm formed by myriads bacteria that have a considerable impact in health and disease. Here, the authors show that biofilm-associated proteins from intestinal microbiota form amyloid-like structures that exacerbate alpha-synuclein pathologies.

    • Ariadna Fernández-Calvet
    • Leticia Matilla-Cuenca
    • Jaione Valle
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19

  • A survey of genetic variation in Native American and Siberian populations reveals that Native Americans are descended from at least three streams of gene flow from Asia: after the initial peopling of the continent there was a southward expansion facilitated by the coast, with sequential population splits and little gene flow after divergence, especially in South America.

    • David Reich
    • Nick Patterson
    • Andrés Ruiz-Linares
    Research
    Nature
    Volume: 488, P: 370-374

  • A non-viral strategy to introduce large DNA sequences into T cells enables the correction of a pathogenic mutation that causes autoimmunity, and the replacement of an endogenous T-cell receptor with an engineered receptor that can recognize cancer antigens.

    • Theodore L. Roth
    • Cristina Puig-Saus
    • Alexander Marson
    Research
    Nature
    Volume: 559, P: 405-409