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Showing 1–5 of 5 results
Advanced filters: Author: Grainne Kearns Clear advanced filters
  • Septic costochondritis is a rare presentation that is usually seen in intravenous drug users, patients with diabetes or those receiving long-term hemodialysis. In this Case Study, the authors describe the diagnosis and management of this condition in a previously healthy patient without any of the established risk factors.

    • Ausaf F. Mohammad
    • Nicky Ambrose
    • Grainne Kearns
    Reviews
    Nature Reviews Rheumatology
    Volume: 5, P: 708-710
  • Mitochondrial diseases are a group of genetic disorders that are characterized by mutations in nuclear or mitochondrial DNA. This Primer discusses the mechanisms underlying the development of mitochondrial diseases, in addition to the diagnosis, prevention and management of these disorders.

    • Gráinne S. Gorman
    • Patrick F. Chinnery
    • Douglass M. Turnbull
    Reviews
    Nature Reviews Disease Primers
    Volume: 2, P: 1-22
  • An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

    • Erola Pairo-Castineira
    • Konrad Rawlik
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 617, P: 764-768