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Showing 1–3 of 3 results
Advanced filters: Author: Gregorius Rustandi Clear advanced filters

  • Highly localized mechanical forces that shape in vivo tissue development remain challenging to recapitulate in vitro. Here the authors use magnetically actuated nanoparticles to generate spatially defined forces within organoids, which guide the spatial organization of tissue patterning and growth.

    • Abdel Rahman Abdel Fattah
    • Niko Kolaitis
    • Adrian Ranga
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • Bioengineering live tissues has remained challenging due to limited nutrient exchange in the growing tissues. Here, the authors have developed micro-perfused 2-photon printing of 3D microfluidics, to engineer large-scale, viable and functional neural and hepatic 3D tissues.

    • Sergei Grebenyuk
    • Abdel Rahman Abdel Fattah
    • Adrian Ranga
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • Mechanical forces, along with gene regulatory networks and cell-cell signalling, play an important role in the complex organization of tissues. Here the authors describe devices that actively apply mechanical force to developing neural tube, demonstrating that mechanical forces increase growth and enhance patterning.

    • Abdel Rahman Abdel Fattah
    • Brian Daza
    • Adrian Ranga
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13