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Showing 1–2 of 2 results
Advanced filters: Author: Gregory W. Busey Clear advanced filters

  • The TRPM7 channel enables endosomal acidification, which is vital for the entry of many enveloped viruses. Here, the authors show that loss of TRPM7 protects cells from various pandemic-threat viruses, pointing to a new strategy for broad-spectrum antiviral drugs.

    • Catherine A. Doyle
    • Gregory W. Busey
    • Bimal N. Desai
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19

  • Efficient removal of apoptotic cells by phagocytosis underlies tissue development, wound repair, host defense and organ homeostasis. Here, authors identify TRPM7 as a regulator of cargo acidification and Ca2+ signaling during apoptotic cell clearance.

    • Michael S. Schappe
    • Marta E. Stremska
    • Bimal N. Desai
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16