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Showing 1–4 of 4 results
Advanced filters: Author: Grigoriy A. Armeev Clear advanced filters

  • Nucleosomes tightly wrap ~147 DNA base pairs around an octamer of histone proteins, but how nucleosome structural dynamics affect genome functioning is not completely clear. Here authors employ all-atom molecular dynamics simulations of nucleosome core particles and observe that octamer dynamics and plasticity enable DNA unwrapping and sliding.

    • Grigoriy A. Armeev
    • Anastasiia S. Kniazeva
    • Alexey K. Shaytan
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Nucleocytoplasmic Large DNA Viruses (NCLDV) that infect algae encode two distinct families of microbial rhodopsins. Here, the authors characterise two proteins form the viral rhodopsin group 1 OLPVR1 and VirChR1, present the 1.4 Å crystal structure of OLPVR1 and show that viral rhodopsins 1 are light-gated cation channels.

    • Dmitrii Zabelskii
    • Alexey Alekseev
    • Valentin Gordeliy
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16

  • spFRET microscopy analysis reveals how FACT reversibly uncoils DNA from nucleosomes during remodeling, thus modulating DNA accessibility in vitro and in vivo.

    • Maria E Valieva
    • Grigoriy A Armeev
    • Alexey V Feofanov
    Research
    Nature Structural & Molecular Biology
    Volume: 23, P: 1111-1116