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Showing 1–9 of 9 results

Advanced filters: Author: Guang-rong Zhao Clear advanced filters

Creation of a eukaryotic multiplexed site-specific inversion system and its application for metabolic engineering

The site-specific DNA inversion system is a versatile tool for genetic engineering. Here, authors developed a multiplexed DNA inversion system, Rci51-5/multi-sfxa101, in eukaryotes, facilitating promoter substitution for metabolic engineering applications.

Jieyi Li
Simiao Gong
Ying-Jin Yuan
ResearchOpen Access24 Feb 2025
Nature Communications

Volume: 16, P: 1-11
Assembly and delivery of large DNA via chromosome elimination in yeast

Here the authors present a protocol for haploidization-mediated DNA assembly and delivery (HAnDy), a CRISPR–Cas9-based, chromosome elimination-mediated method that enables efficient Mb-scale DNA assembly and delivery in yeast.

Yuan Ma
Yao Xiong
Ying-jin Yuan
Protocols10 Jul 2025
Nature Protocols

P: 1-28
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder

Our combined large-scale neuroimaging and brain transcriptome study demonstrates genetic substrates underlying cortical functional abnormalities in depression, suggesting transcriptomic decoding of regional cortical vulnerability to depression.

Jiajia Zhu
Xiao Chen
Yongqiang Yu
ResearchOpen Access08 Aug 2024
Communications Biology

Volume: 7, P: 1-12
Pretreatment with broad-spectrum antibiotics alters the pharmacokinetics of major constituents of Shaoyao-Gancao decoction in rats after oral administration

Meng Liu
Jie Yuan
Jia Liu
Research17 May 2018
Acta Pharmacologica Sinica

Volume: 40, P: 288-296
K88 acetylation of FTO increases its RNA m⁶A demethylation and promotes tumorigenesis

Jing Li
Xinxin Zhang
Guang-Rong Yan
Research19 Jun 2025
Oncogene

Volume: 44, P: 3014-3024
Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder

Yu-Dan Ding
Xiao Chen
Wen-Bin Guo
ResearchOpen Access06 Jun 2022
Translational Psychiatry

Volume: 12, P: 1-9
Disrupted intrinsic functional brain topology in patients with major depressive disorder

Hong Yang
Xiao Chen
Chao-Gan Yan
ResearchOpen Access12 Aug 2021
Molecular Psychiatry

Volume: 26, P: 7363-7371
Connectomics-based resting-state functional network alterations predict suicidality in major depressive disorder

Qing Wang
Cancan He
Yu-Feng Zang
ResearchOpen Access27 Nov 2023
Translational Psychiatry

Volume: 13, P: 1-12
Aberrant resting-state co-activation network dynamics in major depressive disorder

Ziqi An
Kai Tang
Yanqiu Feng
ResearchOpen Access03 Jan 2024
Translational Psychiatry

Volume: 14, P: 1-12