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Showing 1–5 of 5 results
Advanced filters: Author: Gudrun F Debes Clear advanced filters

  • Il-10-expressing B cells play a pivotal role in immune homeostasis, but little is known about the factors and pathways that affect the development of this heterologous population of regulatory B cells. Here authors show in a mouse model that in embryonic life, soluble IgM restrains the expansion of Il-10-positive B cells, via utilizing FcµR and other putative receptors.

    • Shannon Eileen McGettigan
    • Lazaro Emilio Aira
    • Gudrun F. Debes
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • The multifarious fates of CD4+ T helper cells mediate helpful and harmful immunity. An unexpected kinship between 'harmful' interleukin 17–producing T helper cells and 'helpful' follicular T helper cells has now been found.

    • Gudrun F Debes
    • Steven L Reiner
    News & Views
    Nature Immunology
    Volume: 10, P: 138-140

  • The migration of TH2 cells into allergy-affected tissue is key to maintaining the inflammatory response. CCR8-CCL8, a newly identified chemokine receptor–ligand pair, mediates the skin accumulation of TH2 cells with the specific potential to drive chronic eosinophilic inflammation.

    • Gudrun F Debes
    • Malissa C Diehl
    News & Views
    Nature Immunology
    Volume: 12, P: 111-112