Nature Search

BMAL1-TRIM28 represses transposable elements independently of CLOCK in pluripotent cells

Here, the authors find that BMAL1, best known for controlling the body clock, partners with TRIM28 in naïve pluripotent stem cells to repress retrotransposons.

Amador Gallardo
Efres Belmonte-Reche
David Landeira
ResearchOpen Access10 Sept 2025
Nature Communications

Volume: 16, P: 1-15
The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition

Human Long INterspersed Element class 1 (LINE-1) elements are expressed and mobilized in many types of cancer, contributing to malignancy. Here the authors show that the tumor suppressor microRNA let-7 targets the LINE-1 mRNA and reduces LINE-1 mobilization.

Pablo Tristán-Ramos
Alejandro Rubio-Roldan
Sara R. Heras
ResearchOpen Access11 Nov 2020
Nature Communications

Volume: 11, P: 1-14
Cloxacillin plus fosfomycin versus cloxacillin alone for methicillin-susceptible Staphylococcus aureus bacteremia: a randomized trial

New treatments are essential for methicillin-susceptible Staphylococcus aureus bacteremia, but progress is slow. In this phase III–IV trial, cloxacillin plus fosfomycin failed to show superiority over cloxacillin alone, underscoring the challenges to improving patient outcomes.

Sara Grillo
Miquel Pujol
Ana Maria Sanchez-Diaz
ResearchOpen Access02 Oct 2023
Nature Medicine

Volume: 29, P: 2518-2525
Exploring the Loss Aversion Scale’s psychometric properties in Spain

Javier Cabedo-Peris
César Merino-Soto
Manuel Martí-Vilar
ResearchOpen Access08 Jul 2024
Scientific Reports

Volume: 14, P: 1-15
Mortality reduction in older COVID-19-patients hospitalized in Spain during the second pandemic wave from the SEMI-COVID-19 Registry

José-Manuel Casas-Rojo
Juan-Miguel Antón-Santos
Hector Meijide Míguez
ResearchOpen Access18 Oct 2023
Scientific Reports

Volume: 13, P: 1-18
Impact of SARS-CoV-2 infection therapies on the risk of venous thromboembolism and cardiovascular events from the SEMI-COVID-19 Registry

Crhistian-Mario Oblitas
Pablo Demelo-Rodríguez
Hector Meijide Míguez
ResearchOpen Access05 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the immune activation induced by previous nivolumab therapy

Juan C. Nieto
Elisa Roldán
Pere Barba
Research11 May 2020
Leukemia

Volume: 34, P: 3420-3425
Assembling a new generation of radiopharmaceuticals with supramolecular theranostics

Supramolecular metal-based structures have immense potential for biomedical applications as multimodal theranostic platforms. This Review gives an overview of the design principles and synthetic strategies; it also highlights the achievements in the field of radiochemistry.

Guillermo Moreno-Alcántar
Marike Drexler
Angela Casini
Reviews28 Oct 2024
Nature Reviews Chemistry

Volume: 8, P: 893-914
The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

An integrated resource of (epi)genomic features in annotated chronic lymphocytic leukemia (CLL) primary samples uncovers subgroup-specific regulatory alterations associated with clinical behavior.

Renée Beekman
Vicente Chapaprieta
Jose I. Martin-Subero
Research21 May 2018
Nature Medicine

Volume: 24, P: 868-880
Pneumoproteins and biomarkers of inflammation and coagulation do not predict rapid lung function decline in people living with HIV

David M. MacDonald
Sarah Samorodnitsky
B. Wade
ResearchOpen Access23 Mar 2023
Scientific Reports

Volume: 13, P: 1-12

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BMAL1-TRIM28 represses transposable elements independently of CLOCK in pluripotent cells

The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition

Cloxacillin plus fosfomycin versus cloxacillin alone for methicillin-susceptible Staphylococcus aureus bacteremia: a randomized trial

Exploring the Loss Aversion Scale’s psychometric properties in Spain

Mortality reduction in older COVID-19-patients hospitalized in Spain during the second pandemic wave from the SEMI-COVID-19 Registry

Impact of SARS-CoV-2 infection therapies on the risk of venous thromboembolism and cardiovascular events from the SEMI-COVID-19 Registry

Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the immune activation induced by previous nivolumab therapy

Assembling a new generation of radiopharmaceuticals with supramolecular theranostics

The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

Pneumoproteins and biomarkers of inflammation and coagulation do not predict rapid lung function decline in people living with HIV

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