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Showing 1–5 of 5 results
Advanced filters: Author: Guillermo Pons-Estel Clear advanced filters

  • Delays in the diagnosis of systemic lupus erythematosus negatively affect the treatment, quality of life and outcomes of affected individuals. In this Perspective, the authors provide an overview of the contributing factors and consequences of diagnostic delay in systemic lupus erythematosus and discuss how this urgent issue should be addressed.

    • Guillermo J. Pons-Estel
    • María Fernanda Ramírez-Flores
    • Ingris Peláez-Ballestas
    Reviews
    Nature Reviews Rheumatology
    Volume: 21, P: 566-574

  • Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong ethnic and gender bias. In a transancestral genetic association study, Langefeldet al. identify 24 novel regions associated with risk to lupus and propose a cumulative hits hypothesis for loci conferring risk to SLE.

    • Carl D. Langefeld
    • Hannah C. Ainsworth
    • Timothy J. Vyse
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-18

  • The new 2019 EULAR–ACR classification criteria for systemic lupus erythematosus (SLE) performed well in the initial derivative and validation cohorts. But do these criteria outperform previous classification criteria across sexes, disease durations or ethnicities?

    • Guillermo J. Pons-Estel
    • Graciela S. Alarcón
    News & Views
    Nature Reviews Rheumatology
    Volume: 17, P: 7-8

  • Differentiating between the early stages of systemic lupus erythematosus (SLE) and undifferentiated connective tissue disease (UCTD) can be challenging. In this Review, the authors summarize current knowledge on UCTD and early-stage SLE and discuss clinical approaches to diagnosing these conditions.

    • Savino Sciascia
    • Dario Roccatello
    • Marta Mosca
    Reviews
    Nature Reviews Rheumatology
    Volume: 18, P: 9-21

  • In this Consensus Statement, the Treatment Response Measure for Systemic Lupus Erythematosus Consortium presents the initial outcomes of a project to develop a clinical outcome assessment that can contribute to the regulatory approval process for therapeutic agents via its incorporation in end points of clinical trials in systemic lupus erythematosus.

    • Kathryn Connelly
    • Laura E. Eades
    • Yulia Pincus
    Reviews
    Nature Reviews Rheumatology
    Volume: 19, P: 592-602