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Genotyping, sequencing and analysis of 140,000 adults from Mexico City

Genotype and exome sequencing of 150,000 participants and whole-genome sequencing of 9,950 selected individuals recruited into the Mexico City Prospective Study constitute a valuable, publicly available resource of non-European sequencing data.

Andrey Ziyatdinov
Jason Torres
Roberto Tapia-Conyer
ResearchOpen Access11 Oct 2023
Nature

Volume: 622, P: 784-793
Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas

Ultrasound-mediated blood-brain barrier opening has been exploited to improve drug delivery in the brain. Here the authors show that low-intensity pulsed ultrasound in combination with intravenous injection of microbubbles enhances the delivery of doxorubicin and anti-PD1 in gliomas, improving anti-tumor immune responses.

Víctor A. Arrieta
Andrew Gould
Adam M. Sonabend
ResearchOpen Access06 Jun 2024
Nature Communications

Volume: 15, P: 1-19
Architecture and evolution of a minute plant genome

The genome of the carnivorous bladderwort plant Utricularia gibba is described here; despite having undergone at least three rounds of whole-genome duplication, its genome is unusually small and virtually devoid of intergenic DNA.

Enrique Ibarra-Laclette
Eric Lyons
Luis Herrera-Estrella
ResearchOpen Access12 May 2013
Nature

Volume: 498, P: 94-98
A covalent creatine kinase inhibitor ablates glioblastoma migration and sensitizes tumors to oxidative stress

Joshua L. Katz
Yuheng Geng
Jason Miska
ResearchOpen Access20 Sept 2024
Scientific Reports

Volume: 14, P: 1-16
Kynurenine Pathway as a New Target of Cognitive Impairment Induced by Lead Toxicity During the Lactation

Daniela Ramirez Ortega
Paulina Ovalle Rodríguez
Verónica Pérez de la Cruz
ResearchOpen Access21 Feb 2020
Scientific Reports

Volume: 10, P: 1-14

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Genotyping, sequencing and analysis of 140,000 adults from Mexico City

Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas

Architecture and evolution of a minute plant genome

A covalent creatine kinase inhibitor ablates glioblastoma migration and sensitizes tumors to oxidative stress

Kynurenine Pathway as a New Target of Cognitive Impairment Induced by Lead Toxicity During the Lactation

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