Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease with wide-ranging clinical manifestations that can involve the CNS and PNS. In this article, Jeltsch-David and Muller review the clinical features and pathogenesis of neuropsychiatric SLE (NPSLE), focusing on the aspects that might aid identification of biomarkers. They also discuss the classification and treatment of NPSLE, and identify avenues for future research.
- Hélène Jeltsch-David
- Sylviane Muller