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Showing 1–50 of 89 results

Advanced filters: Author: H Kitano Clear advanced filters

Binding of a non-β-lactam antibiotic to penicillin-binding proteins

Y. Nozaki
N. Katayama
Y. Nakao
Research08 Jan 1987
Nature

Volume: 325, P: 179-180
Interpreting the anholonomy of coiled light

M. V. Berry
Research25 Mar 1987
Nature

Volume: 326, P: 277-278
Anion vacancies activate N₂ to ammonia on Ba–Si orthosilicate oxynitride-hydride

N₂ reduction to ammonia typically requires transition metal catalysts, proceeding via a strong metal–nitrogen interaction. Now a Ba–Si orthosilicate oxynitride–hydride has been shown to function as a transition-metal-free catalyst for ammonia synthesis through an anion-vacancy-mediated mechanism, where electrons at the vacancy sites facilitate N₂ activation.

Zhujun Zhang
Kazuki Miyashita
Masaaki Kitano
ResearchOpen Access17 Feb 2025
Nature Chemistry

Volume: 17, P: 679-687
Stress dependence of the mechanism of the olivine–spinel transformation

P. C. Burnley
H. W. Green II
Research27 Apr 1989
Nature

Volume: 338, P: 753-756
Increased iron uptake by splenic hematopoietic stem cells promotes TET2-dependent erythroid regeneration

The cues guiding hematopoietic stem cells (HSCs) to regenerate specific cell types lost due to injury remain elusive. This study shows that iron instructs erythroid differentiation of HSCs during anemia in a Tet2-dependent manner.

Yu-Jung Tseng
Yuki Kageyama
Daisuke Nakada
ResearchOpen Access15 Jan 2024
Nature Communications

Volume: 15, P: 1-16
Emergent patterns of patchiness differ between physical and planktonic properties in the ocean

What can we learn from spatial patterns in the ocean? This study suggests planktonic patterns are uncorrelated from physical patchiness, poorly captured from satellite observations, and an underutilized window into ocean biogeochemistry.

Patrick Clifton Gray
Emmanuel Boss
Yoav Lehahn
ResearchOpen Access20 Feb 2025
Nature Communications

Volume: 16, P: 1-12
Mechanisms of simultaneous linear and nonlinear computations at the mammalian cone photoreceptor synapse

Cone photoreceptors signal to several bipolar cell types at one of the most structurally complex synapses in the central nervous system. Here, the authors show how the 3D organization of this synapse creates different signals in the postsynaptic OFF bipolar cell types.

Chad P. Grabner
Daiki Futagi
Steven H. DeVries
ResearchOpen Access16 Jun 2023
Nature Communications

Volume: 14, P: 1-19
Author Correction: Mechanisms of simultaneous linear and nonlinear computations at the mammalian cone photoreceptor synapse

Chad P. Grabner
Daiki Futagi
Steven H. DeVries
Amendments and CorrectionsOpen Access20 Mar 2024
Nature Communications

Volume: 15, P: 1
Effect of Lipoic Acid in a Patient with Defective Activity of Pyruvate Dehydrogenase, 2-Oxoglutarate Dehydrogenase, and Branched- Chain Keto Acid Dehydrogenase

I Yoshida
L Sweetman
B H Robinson
Research01 Jan 1990
Pediatric Research

Volume: 27, P: 75-79
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are preferentially found at repeats with high transcription initiation level.

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
ResearchOpen Access02 Jun 2021
Nature Communications

Volume: 12, P: 1-18
A mutant gibberellin-synthesis gene in rice

New insight into the rice variant that helped to avert famine over thirty years ago.

A. Sasaki
M. Ashikari
M. Matsuoka
Research18 Apr 2002
Nature

Volume: 416, P: 701-702
The N⁶-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity

In this work, Yoshinaga et al. use functional CRISPR screens and in vivo analyses to show that an RNA methyltransferase METTL16 and MTR4-nuclear exosome play an essential role in maintaining erythropoiesis and regulating DNA repair in erythroblasts.

Masanori Yoshinaga
Kyuho Han
Osamu Takeuchi
ResearchOpen Access28 Oct 2022
Nature Communications

Volume: 13, P: 1-17
Language anxiety in an Algerian multilingual tertiary context

Abdo Hasan AL-Qadri
Mohammad H. Al-khresheh
Amira Bouflih
ResearchOpen Access08 Mar 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-9
Multiple karyotype differences between populations of the Hoplias malabaricus (Teleostei; Characiformes), a species complex in the gray area of the speciation process

Fernando H. S. Souza
Manolo F. Perez
Marcelo B. Cioffi
Research22 Jul 2024
Heredity

Volume: 133, P: 216-226
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Resistance to first line treatment is a major hurdle in cancer treatment, that can be overcome with drug combinations. Here, the authors provide a large drug combination screen across cancer cell lines to benchmark crowdsourced methods and to computationally predict drug synergies.

Michael P. Menden
Dennis Wang
Julio Saez-Rodriguez
ResearchOpen Access17 Jun 2019
Nature Communications

Volume: 10, P: 1-17
DNA sequence and comparative analysis of chimpanzee chromosome 22

H. Watanabe
A. Fujiyama
Y. Sakaki
Research27 May 2004
Nature

Volume: 429, P: 382-388
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

Chiea Chuen Khor, Tin Aung, Francesca Pasutto, Janey Wiggs and colleagues report a global genome-wide association study of exfoliation syndrome and a fine-mapping analysis of a previously identified disease-associated locus, LOXL1. They identify a rare protective variant in LOXL1 exclusive to the Japanese population and five new common variant susceptibility loci.

Tin Aung
Mineo Ozaki
Chiea Chuen Khor
Research29 May 2017
Nature Genetics

Volume: 49, P: 993-1004
Effects of nitrogen vacancy sites of oxynitride support on the catalytic activity for ammonia decomposition

Oxynitride-supported Ni catalysts exhibit much higher activity than oxide-supported Ni catalysts for ammonia decomposition reaction. Ammonia is activated at nitrogen vacancy sites on the surface of oxynitride in close vicinity to the supported Ni nanoparticles rather than on the Ni surface, and therefore the catalytic performance is dominated by ease of nitrogen vacancy formation on the catalyst surface.

Kazuki Miyashita
Kiya Ogasawara
Masaaki Kitano
ResearchOpen Access18 Oct 2024
NPG Asia Materials

Volume: 16, P: 1-9
Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

Shyam Prabhakar, Paul Robson, Iain Beehuat Tan and colleagues characterize the cellular heterogeneity of colorectal tumors and their microenvironment on the basis of single-cell RNA–seq data analyzed with their newly developed clustering algorithm, reference component analysis (RCA). Their analyses identify two subtypes of cancer-associated fibroblasts and further divide tumors into subgroups with divergent survival probabilities.

Huipeng Li
Elise T Courtois
Shyam Prabhakar
Research20 Mar 2017
Nature Genetics

Volume: 49, P: 708-718
Major hepatic resection may suppress the growth of tumours remaining in the residual liver

H Yokoyama
S Goto
S Kitano
ResearchOpen Access19 Sept 2000
British Journal of Cancer

Volume: 83, P: 1096-1101
Cure for a crisis?

The first look at the three-dimensional structure of an essential penicillin binding protein from a human pathogen, and its complex with a β-lactam antibiotic provides hope for the future design of improved antibiotics.

Andy-Mark W. H. Thunnissen
Bauke W. Dijkstra
News & Views01 Mar 1996
Nature Structural Biology

Volume: 3, P: 218-221
Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development

C Amendt
P Schirmacher
M Blessing
Research14 Jul 1998
Oncogene

Volume: 17, P: 25-34
Effects of Fetal Tracheal Occlusion (TO) on Alveolar Type 2 Cell Number and Maturation in the Rat

Yoshihiro Kitano
Daniel Von Allmen
Susan H Guttentag
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 307
Successful treatment of bcr/abl-positive acute mixed lineage leukemia by unmanipulated bone marrow transplantation from an HLA-haploidentical (3-antigen-mismatched) cousin

K Ikegame
C Mukouchi
H Ogawa
Research10 Jun 2003
Bone Marrow Transplantation

Volume: 31, P: 1165-1168
Clinical significance of transmembrane 4 superfamily in colon cancer

H Hashida
A Takabayashi
M Miyake
ResearchOpen Access01 Jul 2003
British Journal of Cancer

Volume: 89, P: 158-167
Frequent allelic loss of the RB, D13S319 and D13S25 locus in myeloid malignancies with deletion/translocation at 13q14 of chromosome 13, but not in lymphoid malignancies

K Tanaka
M Arif
N Kamada
Research09 Sept 1999
Leukemia

Volume: 13, P: 1367-1373
p53 Mutations in non-small-cell lung cancers occurring in individuals without a past history of active smoking

Y Takagi
H Osada
T Takahashi
Research01 May 1998
British Journal of Cancer

Volume: 77, P: 1568-1572
Inferring causal molecular networks: empirical assessment through a community-based effort

The HPN-DREAM community challenge assessed the ability of computational methods to infer causal molecular networks, focusing specifically on the task of inferring causal protein signaling networks in cancer cell lines.

Steven M Hill
Laura M Heiser
Sach Mukherjee
ResearchOpen Access22 Feb 2016
Nature Methods

Volume: 13, P: 310-318
Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma

A Ohtsu
H Baba
T Taguchi
ResearchOpen Access20 Jun 2000
British Journal of Cancer

Volume: 83, P: 141-145
Providing Natural Water Structure Surrounding Highly Mobile Maltose Groups Conjugated with Polyrotaxanes

Hiroaki Hirose
Haruyuki Sano
Nobuhiko Yui
Research30 Aug 2006
Polymer Journal

Volume: 38, P: 1093-1097
Distinct genetic involvement of the TP53 gene in therapy-related leukemia and myelodysplasia with chromosomal losses of Nos 5 and/or 7 and its possible relationship to replication error phenotype

S Horiike
S Misawa
M Taniwaki
Research09 Aug 1999
Leukemia

Volume: 13, P: 1235-1242
Nuclear translocation of beta-catenin in colorectal cancer

M Kobayashi
T Honma
H Asakura
ResearchOpen Access21 Apr 2000
British Journal of Cancer

Volume: 82, P: 1689-1693
HLA-DR antigen expression on colorectal carcinomas: influence of expression by IFN-γ in situ and its association with tumour progression

K Matsushita
T Takenouchi
K Isono
Research01 Mar 1996
British Journal of Cancer

Volume: 73, P: 644-648
Single-locus sex determination in the parasitoid wasp Cotesia glomerata (Hymenoptera: Braconidae)

Y Zhou
H Gu
S Dorn
Research19 Apr 2006
Heredity

Volume: 96, P: 487-492
A novel LDLR mutation, H190Y, in a Utah kindred with familial Hypercholesterolemia

P. N. Hopkins
L. L. Wu
R.R. Williams (posthumous)
Research01 Oct 1999
Journal of Human Genetics

Volume: 44, P: 364-367
Adsorbed Block Copolymer Layers: Assembly and Tailoring of Polymer Brushes

M Tirrell
E Parsonage
S Dhoot
Research01 May 1991
Polymer Journal

Volume: 23, P: 641-649
Prognostic significance of angiogenesis in human pancreatic cancer

N Ikeda
M Adachi
M Miyake
ResearchOpen Access26 Feb 1999
British Journal of Cancer

Volume: 79, P: 1553-1563
Protoplast Fusion and Gene Recombination in the Uncommon Actinomycete Planobispora rosea Producing GE2270

Fabrizio Beltrametti
Daniele Barucco
Flavia Marinelli
Research01 Jul 2007
The Journal of Antibiotics

Volume: 60, P: 447-454
Loss of High-Frequency Brain Electrical Response to Thiopental Administration in Alzheimer's-Type Dementia

Daniel P Holschneider
Andrew F Leuchter
Susan Rosenberg-Thompson
Research01 Apr 1997
Neuropsychopharmacology

Volume: 16, P: 269-275
Construction of TUATinsecta database that integrated plant and insect database for screening phytophagous insect metabolic products with medicinal potential

Wakana Nakane
Hisashi Nakamura
Hiroko Tabunoki
ResearchOpen Access15 Oct 2020
Scientific Reports

Volume: 10, P: 1-11
Comparative studies of suppression of malignant cancer cell phenotype by antisense oligo DNA and small interfering RNA

N Hiroi
A Funahashi
H Kitano
Research05 Aug 2005
Cancer Gene Therapy

Volume: 13, P: 7-12
Aberrant expression and phosphorylation of β-catenin in human colorectal cancer

T Takayama
H Shiozaki
M Monden
Research01 Feb 1998
British Journal of Cancer

Volume: 77, P: 605-613
Low BCL-2 expression in acute leukemia with t(8;21) chromosomal abnormality

M Shikami
H Miwa
K Kita
Research10 Mar 1999
Leukemia

Volume: 13, P: 358-368
Rapid imaging of lung cancer using a red fluorescent probe to detect dipeptidyl peptidase 4 and puromycin-sensitive aminopeptidase activities

Shun Kawashima
Daisuke Yoshida
Jun Nakajima
ResearchOpen Access01 Jun 2022
Scientific Reports

Volume: 12, P: 1-12
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
Amendments and CorrectionsOpen Access01 Mar 2022
Nature Communications

Volume: 13, P: 1
Expression of multiple cancer-testis antigen genes in gastrointestinal and breast carcinomas

K Mashino
N Sadanaga
M Mori
ResearchOpen Access28 Aug 2001
British Journal of Cancer

Volume: 85, P: 713-720
Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer

M Kawahara
K Furuse
H Niitani
ResearchOpen Access02 Oct 2001
British Journal of Cancer

Volume: 85, P: 939-943
Clinical and biological characteristics of acute promyelocytic leukemia in Taiwan: a high relapse rate in patients with high initial and peak white blood cell counts during all-trans retinoic acid treatment

W-C Chou
J-L Tang
H-F Tien
Research01 Jul 1997
Leukemia

Volume: 11, P: 921-928
Rapid αβ TCR-mediated responses in γδ T cells transduced with cancer-specific TCR genes

A Hiasa
H Nishikawa
H Shiku
Research26 Feb 2009
Gene Therapy

Volume: 16, P: 620-628
Apoptosis and p53 status predict the efficacy of postoperative administration of UFT in non-small cell lung cancer

F Tanaka
Y Otake
H Wada
ResearchOpen Access16 Jan 2001
British Journal of Cancer

Volume: 84, P: 263-269

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