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Showing 1–50 of 103 results

Advanced filters: Author: H. RECK Clear advanced filters

Upregulation of RECK gene expression by small double-stranded RNA targeting the promoter region

F Sakurai
Y Nanjo
H Mizuguchi
Research28 Mar 2014
Cancer Gene Therapy

Volume: 21, P: 164-170
Involvement of the SKP2–p27^KIP1 pathway in suppression of cancer cell proliferation by RECK

Y Yoshida
K Ninomiya
M Noda
Research12 Dec 2011
Oncogene

Volume: 31, P: 4128-4138
Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells

K Kato
N K Long
T Shibata
ResearchOpen Access29 Jul 2008
British Journal of Cancer

Volume: 99, P: 647-654
The membrane-anchored metalloproteinase regulator RECK stabilizes focal adhesions and anterior–posterior polarity in fibroblasts

Y Morioka
J Monypenny
M Noda
Research26 Jan 2009
Oncogene

Volume: 28, P: 1454-1464
Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs

F Loayza-Puch
Y Yoshida
M Noda
Research15 Feb 2010
Oncogene

Volume: 29, P: 2638-2648
STAT3 upregulates miR-92a to inhibit RECK expression and to promote invasiveness of lung cancer cells

H-Y Lin
C-H Chiang
W-C Hung
ResearchOpen Access02 Jul 2013
British Journal of Cancer

Volume: 109, P: 731-738
TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118

J Oh
T Diaz
W G Stetler-Stevenson
Research20 Feb 2006
Oncogene

Volume: 25, P: 4230-4234
National Needs (II.)

H. E. A.
News26 Dec 1931
Nature

Volume: 128, P: 1053-1055
Pleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progression

M D Bullock
K M Pickard
A H Mirnezami
ResearchOpen Access20 Jun 2013
Cell Death & Disease

Volume: 4, P: e684
Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge

Using cryo-EM, Karasmanis, Reimer, and Kendrick et al. reveal a Lis1-mediated dynein dimer, termed Chi, that serves as intermediate state in relieving dynein’s autoinhibition.

Eva P. Karasmanis
Janice M. Reimer
Andres E. Leschziner
ResearchOpen Access24 Aug 2023
Nature Structural & Molecular Biology

Volume: 30, P: 1357-1364
Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling

Wnt signaling is known to regulate the formation of the blood-brain barrier. Here Hübner et al. dissect the underlying mechanisms using high resolution live imaging in zebrafish, and find that Wnt regulates anastomosis of angiogenic sprouts in the brain by counteracting sphingosine-1-phosphate receptor signaling.

Kathleen Hübner
Pauline Cabochette
Wiebke Herzog
ResearchOpen Access19 Nov 2018
Nature Communications

Volume: 9, P: 1-17
Network analysis of gene expression reveals regulators of cell viscosity and mechanical phenotype

Katherine M. Young
Nicole Latka
Todd Sulchek
ResearchOpen Access30 Sept 2025
Scientific Reports

Volume: 15, P: 1-18
Lubricating Oils and Cancer

J. B. SPEAKMAN
N. H. CHAMBERLAIN
Research15 Oct 1932
Nature

Volume: 130, P: 578-579
Gpr124 is essential for blood–brain barrier integrity in central nervous system disease

The G-protein-coupled receptor GPR124, acting through the canonical Wnt pathway, is required for the maintenance of blood–brain barrier function in mouse models of stroke and glioblastoma.

Junlei Chang
Michael R Mancuso
Calvin J Kuo
Research13 Mar 2017
Nature Medicine

Volume: 23, P: 450-460
Properties of the Organic Microstructures of Some Carbonaceous Chondrites

MICHAEL H. BRIGGS
Research15 Sept 1962
Nature

Volume: 195, P: 1076-1077
Age of Bed I, Olduvai Gorge, Tanganyika

L. S. B. LEAKEY
J. F. EVERNDEN
G. H. CURTIS
Research01 Jul 1961
Nature

Volume: 191, P: 478-479
The Oldoway Human Skeleton

L. S. B. LEAKEY
H. RECK
J. D. SOLOMON
Research18 Mar 1933
Nature

Volume: 131, P: 397-398
Latency of Seedlings in some Grasses

H. G. CHIPPINDALE
Research26 Dec 1931
Nature

Volume: 128, P: 1075-1076
Differential expression of degradome components in cutaneous squamous cell carcinomas

Nijaguna B Prasad
Anne C Fischer
Anthony P Tufaro
Research20 Dec 2013
Modern Pathology

Volume: 27, P: 945-957
Cryo-EM captures early intermediate steps in dynein activation by LIS1

The molecular motor dynein is modulated by several protein regulators, including LIS1. Here, authors use cryo-EM to show how LIS1 activates dynein by disrupting its autoinhibition and stabilizing intermediate states required to assemble the complexes that mediate transport.

Kendrick H. V. Nguyen
Eva P. Karasmanis
Andres E. Leschziner
ResearchOpen Access01 Aug 2025
Nature Communications

Volume: 16, P: 1-11
Bleeding events in bevacizumab-treated cancer patients who received full-dose anticoagulation and remained on study

N B Leighl
J Bennouna
H Hurwitz
ResearchOpen Access18 Jan 2011
British Journal of Cancer

Volume: 104, P: 413-418
Effects of 5-Hydroxytryptamine on Platelet Aggregation

H. R. BAUMGARTNER
G. V. R. BORN
Research13 Apr 1968
Nature

Volume: 218, P: 137-141
Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles

The genomic landscape of hereditary SDHB-mutant pheochromocytomas (PC) and paragangliomas (PG) remains to be explored. Here, the authors perform multiomic analysis on 94 tumours from 79 patients and identify the molecular features of metastatic disease and treatment response.

Aidan Flynn
Andrew D. Pattison
Richard W. Tothill
ResearchOpen Access17 Mar 2025
Nature Communications

Volume: 16, P: 1-20
Multiple steps of dynein activation by Lis1 visualized by cryo-EM

Using cryo-EM, Kendrick et al. reveal multiple dynein conformations during dynein’s mechanochemical cycle and Lis1 binding that represent intermediate states of dynein’s activation.

Agnieszka A. Kendrick
Kendrick H. V. Nguyen
Andres E. Leschziner
ResearchOpen Access23 May 2025
Nature Structural & Molecular Biology

Volume: 32, P: 1434-1444
Early vision and texture perception

James R. Bergen
Edward H. Adelson
Research26 May 1988
Nature

Volume: 333, P: 363-364
MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme

J Lin
S Teo
S Wang
ResearchOpen Access04 Oct 2012
Cell Death & Disease

Volume: 3, P: e398
Gene Similarity of the Triticinae and the Study of Segmental Interchanges

H. N. BARBER
C. J. DRISCOLL
R. S. VICKERY
Research31 May 1969
Nature

Volume: 222, P: 897-898
A New Mountain of the Bell

H. CARRINGTON BOLTON
Research09 May 1889
Nature

Volume: 40, P: 35
The Oldoway Human Skeleton

P. G. H. BOSWELL
Research13 Aug 1932
Nature

Volume: 130, P: 237-238
Theory of Complex Atoms

D. R. H.
News26 Dec 1936
Nature

Volume: 138, P: 1080-1082
Whole genome expression profiling of advance stage papillary serous ovarian cancer reveals activated pathways

Howard Donninger
Tomas Bonome
Michael J Birrer
Research13 Sept 2004
Oncogene

Volume: 23, P: 8065-8077
Tucatinib and trastuzumab in HER2-mutated metastatic breast cancer: a phase 2 basket trial

In this phase 2 basket trial, patients with heavily pretreated HER2-mutated metastatic breast cancer received the small-molecule HER2 inhibitor tucatinib and anti-HER2 trastuzumab, leading to encouraging clinical response rates.

Alicia F. C. Okines
Giuseppe Curigliano
Paula R. Pohlmann
ResearchOpen Access17 Jan 2025
Nature Medicine

Volume: 31, P: 909-916
Influence of atmospheric CO₂ on the decline of C4 plants during the last deglaciation

David R. Cole
H. Curtis Monger
Research07 Apr 1994
Nature

Volume: 368, P: 533-536
Peptide oligomers for holographic data storage

Rolf H. Berg
Søren Hvilsted
P. S. Ramanujam
Research10 Oct 1996
Nature

Volume: 383, P: 505-508
Deep learning with coherent nanophotonic circuits

Programmable silicon nanophotonic processor empowers optical neural networks.

Yichen Shen
Nicholas C. Harris
Marin Soljačić
Research12 Jun 2017
Nature Photonics

Volume: 11, P: 441-446
Recombination in HIV-1

David L. Robertson
Paul M. Sharp
Beatrice H. Hahn
Research09 Mar 1995
Nature

Volume: 374, P: 124-126
Letter

S Winder
D W Noble
W H Church
Correspondence01 May 1998
Eye

Volume: 12, P: 486-488
Comprehensive profiling and localisation of the matrix metalloproteinases in urothelial carcinoma

M J Wallard
C J Pennington
J D Kelly
ResearchOpen Access07 Feb 2006
British Journal of Cancer

Volume: 94, P: 569-577
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance

Targeted protein degradation (TPD) is a key modality for drug discovery. Here the authors present the discovery and analysis of reversible DCAF1-PROTACs, which show efficacy in cellular environments resistant to VHL-PROTACs or with acquired resistance to CRBN-PROTACs.

Martin Schröder
Martin Renatus
Claudio R. Thoma
ResearchOpen Access04 Jan 2024
Nature Communications

Volume: 15, P: 1-19
Molecular Biology at Spetsai

H. Andersen
P. R. Avner
F. R. Williams
Correspondence13 Sept 1969
Nature

Volume: 223, P: 1186
Phase I study of BIBF 1120 with docetaxel and prednisone in metastatic chemo-naive hormone-refractory prostate cancer patients

G Bousquet
J Alexandre
E Raymond
ResearchOpen Access25 Oct 2011
British Journal of Cancer

Volume: 105, P: 1640-1645
Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes

Structural and functional characterization of tetracycline-inactivating enzymes reveals that inhibitors act by locking the enzyme in an unproductive state by restricting substrate-driven conformational dynamics that are important for catalysis.

Jooyoung Park
Andrew J Gasparrini
Niraj H Tolia
Research08 May 2017
Nature Chemical Biology

Volume: 13, P: 730-736
Affinity-optimizing enhancer variants disrupt development

Low-affinity transcription factor binding sites are prevalent across the genome, and single nucleotide changes that increase binding affinity even slightly can cause gain-of-function gene expression and phenotypes (such as polydactyly).

Fabian Lim
Joe J. Solvason
Emma K. Farley
ResearchOpen Access17 Jan 2024
Nature

Volume: 626, P: 151-159
Studies in Infant and Child Mortality

R. T. H.
News22 Nov 1917
Nature

Volume: 100, P: 226-227
The Nickel Industry

H. C. H. CARPENTER
News22 Nov 1917
Nature

Volume: 100, P: 225-226
New Zealand Petrography ¹

A. H.
News18 Jul 1907
Nature

Volume: 76, P: 303
SMAD2 linker phosphorylation impacts overall survival, proliferation, TGFβ1-dependent gene expression and pluripotency-related proteins in NSCLC

Dörte Nitschkowski
Tim Vierbuchen
Sebastian Marwitz
ResearchOpen Access03 May 2025
British Journal of Cancer

Volume: 133, P: 52-65
A phase II multicentre study of ziv-aflibercept in combination with cisplatin and pemetrexed in patients with previously untreated advanced/metastatic non-squamous non-small cell lung cancer

H Chen
M R Modiano
H A Wakelee
ResearchOpen Access28 Nov 2013
British Journal of Cancer

Volume: 110, P: 602-608
She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain

Dynein is a microtubule motor the motility of which is affected by the microtubule-associated protein She1. Here, the authors show that She1 alters dynein stepping behavior and increases its microtubule affinity through simultaneous interactions with the microtubule and dynein microtubule binding domain.

Kari H. Ecklund
Tatsuya Morisaki
Steven M. Markus
ResearchOpen Access15 Dec 2017
Nature Communications

Volume: 8, P: 1-16
MicroRNA signatures characterize multiple myeloma patients

S L Corthals
S M Sun
P Sonneveld
Correspondence24 Jun 2011
Leukemia

Volume: 25, P: 1784-1789

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