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Showing 1–2 of 2 results
Advanced filters: Author: Hai Zemmour Clear advanced filters

  • The detection of cardiomyocyte death is a critical aspect in the diagnosis and monitoring of heart diseases. Here the authors show that cardiomyocyte-specific methylation patterns of circulating cell-free DNA may serve as a biomarker of cardiac cell death in infarcted and septic patients.

    • Hai Zemmour
    • David Planer
    • Yuval Dor
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-9

  • The methylation status of circulating cell-free DNA (cfDNA) can be informative about recent cell death events. Here the authors present an approach to determine the tissue origins of cfDNA, using a reference methylation atlas of 25 human tissues and cell types, and find that cfDNA from patients reveals tissue contributions that agree with clinical findings.

    • Joshua Moss
    • Judith Magenheim
    • Yuval Dor
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12