Nature Search

Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling

Caspase-2 is constitutively expressed in neurons yet its physiological function is not known. Here, the authors report a role for Caspase-2 activity in synaptic plasticity via a reduction in dendritic spine density through cleavage of Rictor suggesting a mechanism to explain the impairments in cognitive flexibility observed in Caspase-2 knockout mice.

Zhi-Xiang Xu
Ji-Wei Tan
Baoji Xu
ResearchOpen Access09 Aug 2019
Nature Communications

Volume: 10, P: 1-13
The best features of diamond nanothread for nanofibre applications

Carbon fibres are emerging as a promising material for multifunctional nanotextiles. Here, the authors show that diamond nanothread possesses excellent torsional deformation capability and interfacial load transfer efficiency, ideal for constructing next generation carbon fibres.

Haifei Zhan
Gang Zhang
Yuantong Gu
ResearchOpen Access17 Mar 2017
Nature Communications

Volume: 8, P: 1-8
Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations

The main cell types involved in autism spectrum disorders through elevated protein synthesis are not well identified. Here, the authors show that overexpression of translation initiation factor eIF4E in microglia results in autism-like behaviour in male, but not female, mice.

Zhi-Xiang Xu
Gyu Hyun Kim
Baoji Xu
ResearchOpen Access14 Apr 2020
Nature Communications

Volume: 11, P: 1-17
Solution-processable, soft, self-adhesive, and conductive polymer composites for soft electronics

Poor adhesion and mechanical mismatches may cause interface failure of soft devices. Here, authors report a supramolecular solvent-doped, soft, adhesive, yet conductive polymer composite for stretchable, wearable, and comfortable electronic devices.

Peng Tan
Haifei Wang
Xuechang Zhou
ResearchOpen Access18 Jan 2022
Nature Communications

Volume: 13, P: 1-12
Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue

Bacterial MutS2, a paralogue of the DNA mismatch-repair protein MutS, is found to bind collided ribosomes and function in translational quality control.

Federico Cerullo
Sebastian Filbeck
Claudio A. P. Joazeiro
Research09 Mar 2022
Nature

Volume: 603, P: 509-514
Refinement of pore size at sub-angstrom precision in robust metal–organic frameworks for separation of xylenes

Separation of xylene isomers is essential for the production of a wide range of materials, but current separation methods are energy intensive. Here the authors report separation of the three xylene isomers at room temperature, via refinement of the pore size in a series of porous MOFs at sub-angstrom precision.

Xiaolin Li
Juehua Wang
Martin Schröder
ResearchOpen Access27 Aug 2020
Nature Communications

Volume: 11, P: 1-10
A distinct entorhinal cortex to hippocampal CA1 direct circuit for olfactory associative learning

Entorhinal cortex transfers multimodal information to hippocampus CA1 neurons via indirect and direct pathways. The authors show that excitatory projections from lateral entorhinal cortex selectively target a subpopulation of morphologically complex, calbindin-expressing pyramidal cells in CA1, forming a distinct direct circuit that is required for olfactory associative learning.

Yiding Li
Jiamin Xu
Xiaohui Zhang
Research06 Mar 2017
Nature Neuroscience

Volume: 20, P: 559-570
High-quality wild barley genome assemblies and annotation with Nanopore long reads and Hi-C sequencing data

Rui Pan
Haifei Hu
Wenying Zhang
ResearchOpen Access10 Aug 2023
Scientific Data

Volume: 10, P: 1-10
Neurotrophin-3 from the dentate gyrus supports postsynaptic sites of mossy fiber-CA3 synapses and hippocampus-dependent cognitive functions

Ji-Wei Tan
Juan Ji An
Baoji Xu
Research11 Jan 2024
Molecular Psychiatry

Volume: 29, P: 1192-1204
Performance Gains in Genome-Wide Association Studies for Longitudinal Traits via Modeling Time-varied effects

Chao Ning
Huimin Kang
Jianfeng Liu
ResearchOpen Access04 Apr 2017
Scientific Reports

Volume: 7, P: 1-12
Difference in post-stress recovery of the gut microbiome and its altered metabolism after chronic adolescent stress in rats

Mengyang Xu
Chen Wang
Jiangjiang Zhu
ResearchOpen Access03 Mar 2020
Scientific Reports

Volume: 10, P: 1-10

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