Nature Search

De novo analysis of bulk RNA-seq data at spatially resolved single-cell resolution

Current methods to reanalyze bulk RNA-seq at spatially resolved single-cell resolution have limitations. Here, the authors develop Bulk2Space, a spatial deconvolution algorithm using single-cell and spatial transcriptomics as references, providing new insights into spatial heterogeneity within bulk tissue.

Jie Liao
Jingyang Qian
Xiaohui Fan
ResearchOpen Access30 Oct 2022
Nature Communications

Volume: 13, P: 1-19
AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation

Dai et al. show that in response to low glucose levels, AMP-activated protein kinase-mediated phosphorylation of WDR24, a component of the GATOR2 complex, leads to suppression of mTORC1 activation.

Xiaoming Dai
Cong Jiang
Wenyi Wei
Research02 Feb 2023
Nature Metabolism

Volume: 5, P: 265-276
Efficient parallelization of tensor network contraction for simulating quantum computation

An efficient method for parallelizing the contraction of tensor networks pushes the boundaries for the classical simulation of quantum computation, and aids the development of quantum algorithms and hardware.

Cupjin Huang
Fang Zhang
Jianxin Chen
ResearchOpen Access13 Sept 2021
Nature Computational Science

Volume: 1, P: 578-587
RcsAB is a major repressor of Yersinia biofilm development through directly acting on hmsCDE, hmsT and hmsHFRS

Nan Fang
Huiying Yang
Ruifu Yang
ResearchOpen Access01 Apr 2015
Scientific Reports

Volume: 5, P: 1-8
Evolutionary selection of biofilm-mediated extended phenotypes in Yersinia pestis in response to a fluctuating environment

Yersinia pestis, the causative agent of plague, can change its biofilm production to influence the dynamics of flea-borne transmission. Here, the authors sequence Y. pestis isolates sampled over 40 years in China and show evidence for climate-associated selection on rpoZ to increase biofilm production.

Yujun Cui
Boris V. Schmid
Ruifu Yang
ResearchOpen Access15 Jan 2020
Nature Communications

Volume: 11, P: 1-8
KDM4B enhances immune surveillance via demethylating cGAS

Qiao Peng
Huimin Zhuo
Meiling Lu
ResearchOpen Access01 Jul 2025
Cell Death & Disease

Volume: 16, P: 1-13
IMP-1 encoded by a novel Tn402-like class 1 integron in clinical Achromobacter xylosoxidans, China

Zhenhong Chen
Haihong Fang
Changting Liu
ResearchOpen Access27 Nov 2014
Scientific Reports

Volume: 4, P: 1-7
EEG β oscillations in aberrant data perception under cognitive load modulation

Haihong Yu
Wei Cao
Guanxiong Pei
ResearchOpen Access03 Oct 2024
Scientific Reports

Volume: 14, P: 1-14
Thermoregulatory response of Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae) to infection by Beauveria bassiana, and its effect on survivorship and reproductive success

Xiaochen Liu
Stuart R. Reitz
Haihong Wang
ResearchOpen Access20 Sept 2019
Scientific Reports

Volume: 9, P: 1-10
PD-L1 expression in lung cancer and its correlation with driver mutations: a meta-analysis

Minghui Zhang
Guoliang Li
Yan Wang
ResearchOpen Access31 Aug 2017
Scientific Reports

Volume: 7, P: 1-10
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation

Zhiya Deng
Maomao Sun
Zhenhua Zeng
ResearchOpen Access26 Feb 2021
Cell Death & Disease

Volume: 12, P: 1-13
Notoginsenoside R1 inhibits vascular smooth muscle cell proliferation, migration and neointimal hyperplasia through PI3K/Akt signaling

Haihong Fang
Shilin Yang
Jun Yu
ResearchOpen Access15 May 2018
Scientific Reports

Volume: 8, P: 1-11
Oscillatory dynamics of p38 activity with transcriptional and translational time delays

Yuan Zhang
Haihong Liu
Jin Zhou
ResearchOpen Access13 Sept 2017
Scientific Reports

Volume: 7, P: 1-11

Search

De novo analysis of bulk RNA-seq data at spatially resolved single-cell resolution

AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation

Efficient parallelization of tensor network contraction for simulating quantum computation

RcsAB is a major repressor of Yersinia biofilm development through directly acting on hmsCDE, hmsT and hmsHFRS

Evolutionary selection of biofilm-mediated extended phenotypes in Yersinia pestis in response to a fluctuating environment

KDM4B enhances immune surveillance via demethylating cGAS

IMP-1 encoded by a novel Tn402-like class 1 integron in clinical Achromobacter xylosoxidans, China

EEG β oscillations in aberrant data perception under cognitive load modulation

Thermoregulatory response of Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae) to infection by Beauveria bassiana, and its effect on survivorship and reproductive success

PD-L1 expression in lung cancer and its correlation with driver mutations: a meta-analysis

SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation

Notoginsenoside R1 inhibits vascular smooth muscle cell proliferation, migration and neointimal hyperplasia through PI3K/Akt signaling

Oscillatory dynamics of p38 activity with transcriptional and translational time delays

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