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Author Correction: PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

Min-Sik Lee
Man-Hyung Jeong
Jaewhan Song
Amendments and CorrectionsOpen Access01 Dec 2020
Nature Communications

Volume: 11, P: 1-2
TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway

The emergence of cisplatin resistance and side-effects are important factors in cancer treatment failure. Here, the authors identify autophagy-mediated EGFR hyperactivation by TRPV1 promotion as a mechanism of cisplatin resistance and demonstrate the efficacy of a TRPV1 inhibitor to sensitize lung cancer to cisplatin.

Se Jin Oh
Ji Yeon Lim
Tae Woo Kim
ResearchOpen Access10 May 2023
Nature Communications

Volume: 14, P: 1-17
PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

Mutations and post-translational modifications of the PI3K/AKT pathway inhibitor PTEN are a feature of many cancers, but these have not been associated with cervical cancer. Here, the authors identify a PI3K/AKT-mediated ubiquitination degradation pathway of PTEN that occurs in patients with cervical cancer.

Min-Sik Lee
Man-Hyung Jeong
Jaewhan Song
ResearchOpen Access17 Jul 2015
Nature Communications

Volume: 6, P: 1-14
HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors

Nanog can confer resistance to cancer immunotherapy by promoting AKT activity. Here, the authors demonstrate that HSP90A is a Nanog target that stabilizes the AKT coactivator TCL1, thereby activating AKT, and that HSP90A inhibition can enhance the anti-tumor efficacy of adoptive T cell transfer and checkpoint blockade.

Kwon-Ho Song
Se Jin Oh
Tae Woo Kim
ResearchOpen Access28 Jan 2020
Nature Communications

Volume: 11, P: 1-16
NANOG confers resistance to complement-dependent cytotoxicity in immune-edited tumor cells through up-regulating CD59

Sung Wook Son
Eunho Cho
Tae Woo Kim
ResearchOpen Access23 May 2022
Scientific Reports

Volume: 12, P: 1-10
Ascitic autotaxin as a potential prognostic, diagnostic, and therapeutic target for epithelial ovarian cancer

Jung-A Choi
Hyosun Kim
Jae-Hoon Kim
ResearchOpen Access18 Aug 2023
British Journal of Cancer

Volume: 129, P: 1184-1194
Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF

Aram Ko
Su Yeon Han
Jaewhan Song
Research22 Feb 2018
Cell Death & Differentiation

Volume: 25, P: 1050-1062
REP1 inhibits FOXO3-mediated apoptosis to promote cancer cell survival

Kwon-Ho Song
Seon Rang Woo
Young-Ki Bae
ResearchOpen Access05 Jan 2017
Cell Death & Disease

Volume: 8, P: e2536
A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue

Joon-Yong Chung
Jiyeon Choi
Stephen M Hewitt
Research22 Aug 2016
Laboratory Investigation

Volume: 96, P: 1116-1127
API5 induces cisplatin resistance through FGFR signaling in human cancer cells

Han Sol Jang
Seon Rang Woo
Tae Woo Kim
ResearchOpen Access08 Sept 2017
Experimental & Molecular Medicine

Volume: 49, P: e374

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