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Advanced filters: Author: Hangjun Ke Clear advanced filters

An essential adaptor for apicoplast fission and inheritance in malaria parasites

This study identifies PfAnchor as an adaptor essential for apicoplast fission and inheritance in malaria parasites, uncovering a parasite-specific mechanism that offers a new avenue for antimalarial intervention.
,

James A. Blauwkamp
Krithika Rajaram
Sabrina Absalon
ResearchOpen Access27 Nov 2025
Nature Communications

Volume: 16, P: 1-18
Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug

Integrated structural biology approach leveraging in situ cryo-electron tomography reveals molecular details of the native malarial translation elongation cycle and its perturbation by cabamiquine, a potent antimalarial drug candidate.

Leonie Anton
Wenjing Cheng
Chi-Min Ho
ResearchOpen Access18 Aug 2025
Nature Structural & Molecular Biology

Volume: 32, P: 2158-2164

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An essential adaptor for apicoplast fission and inheritance in malaria parasites

Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug

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