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Showing 1–4 of 4 results
Advanced filters: Author: Hans-Georg Joost Clear advanced filters

  • High consumption of red meat is associated with an increased risk of type 2 diabetes mellitus, but the causality of the association is difficult to prove. Nevertheless, the findings of a large study of changes in red meat consumption add important evidence, consistent with causality of this association.

    • Hans-Georg Joost
    News & Views
    Nature Reviews Endocrinology
    Volume: 9, P: 509-511

  • It has been a long-held belief that the hormone ghrelin is activated when an animal is hungry, inducing the brain to increase food intake. Now, Matthias Tschöp and his colleagues show in vivo that it is not the deficiency of calories per se that activates ghrelin, but rather the presence of energy-rich medium-chain dietary fats.

    • Henriette Kirchner
    • Jesus A Gutierrez
    • Matthias H Tschöp
    Research
    Nature Medicine
    Volume: 15, P: 741-745

  • Hadi Al-Hasani and colleagues report that a frameshift deletion in Tbc1d1 in lean SJL mice underlies a quantitative trait locus conferring protection against high-fat diet-induced obesity. TBC1D1 seems to influence metabolism by regulating fatty acid uptake and oxidation in skeletal muscle cells.

    • Alexandra Chadt
    • Katja Leicht
    • Hadi Al-Hasani
    Research
    Nature Genetics
    Volume: 40, P: 1354-1359