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Showing 1–5 of 5 results
Advanced filters: Author: Harry Wischnewski Clear advanced filters
  • The neural mechanisms underpinning phase precession remain poorly understood. Here, the authors demonstrate that exogenously generated oscillatory electric fields in the brain can induce phase precession-like effects on cortical excitability and neural firing.

    • Miles Wischnewski
    • Harry Tran
    • Alexander Opitz
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15
  • The authors report an unusual mode of AU-rich RNA recognition by the RNA recognition motifs of DND1, a protein essential for germline development, in a 27.5 kDa NMR structure and provide additional insight on DND1 function from cell-based experiments.

    • Malgorzata M. Duszczyk
    • Harry Wischnewski
    • Frédéric H.-T. Allain
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17
  • In cancer cells, telomeres can be elongated through homology directed-repair pathways in a process known as Alternative Lengthening of Telomeres (ALT). Here, the authors reveal that FANCM regulates ALT activity and ALT cell proliferation by limiting the activity of uncontrolled BLM and telomeric R-loops.

    • Bruno Silva
    • Richard Pentz
    • Claus M. Azzalin
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-16
  • A subset of cancers maintains telomere length independently of telomerase by activating alternative lengthening of telomeres (ALT) pathways. Here the authors show that RNaseH1 modulates telomeric homologous recombination frequencies in ALT cells by regulating the levels of RNA–DNA hybrids between TERRA and telomeric DNA.

    • Rajika Arora
    • Yongwoo Lee
    • Claus M. Azzalin
    ResearchOpen Access
    Nature Communications
    Volume: 5, P: 1-11