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Showing 1–3 of 3 results

Advanced filters: Author: Hasier Eraña Clear advanced filters

A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions

To study neurodegenerative prion diseases, a method (PMSA) for generating prions spontaneously is presented. Applied to 380+ different prion proteins, their tendency to become pathogenic was ranked, illuminating their formation process.

Hasier Eraña
Cristina Sampedro-Torres-Quevedo
Joaquín Castilla
ResearchOpen Access08 Mar 2024
Nature Communications

Volume: 15, P: 1-14
Post-translational modifications in PrP expand the conformational diversity of prions in vivo

Patricia Aguilar-Calvo
Xiangzhu Xiao
Christina J. Sigurdson
ResearchOpen Access08 Mar 2017
Scientific Reports

Volume: 7, P: 1-15
Generation of a new infectious recombinant prion: a model to understand Gerstmann–Sträussler–Scheinker syndrome

Saioa R. Elezgarai
Natalia Fernández-Borges
Joaquín Castilla
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-18