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Showing 1–6 of 6 results

Advanced filters: Author: Hayato Anzawa Clear advanced filters

Author Correction: PNPO–PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity

Hiroki Sekine
Haruna Takeda
Hozumi Motohashi
Amendments and CorrectionsOpen Access26 Nov 2024
Nature Metabolism

Volume: 6, P: 2391
Publisher Correction: Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers

Keito Okazaki
Hayato Anzawa
Hozumi Motohashi
Amendments and CorrectionsOpen Access15 Jan 2021
Nature Communications

Volume: 12, P: 1
PNPO–PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity

Sekine et al. show that macrophages utilize different pathways to sense acute and chronic hypoxia, the latter relying preferentially on PNPO–PLP rather than hypoxia-inducible factors.

Hiroki Sekine
Haruna Takeda
Hozumi Motohashi
ResearchOpen Access31 May 2024
Nature Metabolism

Volume: 6, P: 1108-1127
Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers

Aberrant activation of NRF2 in cancer cells contributes to tumorigenicity and therapeutic resistance. Here, the authors show that NRF2 cooperates with CEBPB and remodels enhancers to confer tumor-initiating activity on NRF2- activated non-small cell lung cancers.

Keito Okazaki
Hayato Anzawa
Hozumi Motohashi
ResearchOpen Access20 Nov 2020
Nature Communications

Volume: 11, P: 1-19
Simulating metabolic pathways to enhance interpretations of metabolome genome-wide association studies

Shun Kodate
Mitsuharu Sato
Kengo Kinoshita
ResearchOpen Access16 May 2025
Scientific Reports

Volume: 15, P: 1-11
Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank

Aye Ko Ko Minn
Motomichi Matsuzaki
Gen Tamiya
ResearchOpen Access03 Apr 2025
Journal of Human Genetics

Volume: 70, P: 287-296