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Showing 1–4 of 4 results
Advanced filters: Author: Hector Roux de Bézieux Clear advanced filters
  • scRNA-Seq has enabled the study of dynamic systems such as response to a drug at the individual cell and gene levels. Here the authors introduce a framework to interpret differences at the trajectory, cell populations, and individual gene levels.

    • Hector Roux de Bézieux
    • Koen Van den Berge
    • Sandrine Dudoit
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16
  • Downstream of trajectory inference for cell lineages based on scRNA-seq data, differential expression analysis yields insight into biological processes. Here, Van den Berge et al. develop tradeSeq, a framework for the inference of within and between-lineage differential expression, based on negative binomial generalized additive models.

    • Koen Van den Berge
    • Hector Roux de Bézieux
    • Lieven Clement
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13
  • The BRAIN Initiative Cell Census Network has constructed a multimodal cell census and atlas of the mammalian primary motor cortex in a landmark effort towards understanding brain cell-type diversity, neural circuit organization and brain function.

    • Edward M. Callaway
    • Hong-Wei Dong
    • Susan Sunkin
    ResearchOpen Access
    Nature
    Volume: 598, P: 86-102