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Advanced filters: Author: Heidar Heidari Khoei Clear advanced filters

  • Blastoids derived from naive PXGL-cultured human pluripotent stem cells in which Hippo, TGF-β and ERK pathways are inhibited closely recapitulate aspects of blastocyst development, form cells resembling blastocyst-stage cells and thus provide a model system for implantation and development studies.

    • Harunobu Kagawa
    • Alok Javali
    • Nicolas Rivron
    ResearchOpen Access
    Nature
    Volume: 601, P: 600-605

  • The authors present a protocol for the generation of human blastoids—structures morphologically and transcriptionally resembling complete blastocysts—from pluripotent stem cells and for their use in modeling implantation into hormonally stimulated endometrial cells.

    • Heidar Heidari Khoei
    • Alok Javali
    • Nicolas Rivron
    Protocols
    Nature Protocols
    Volume: 18, P: 1584-1620