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Showing 1–2 of 2 results
Advanced filters: Author: Helene L. Andrews-Polymenis Clear advanced filters

  • Retron-Sen2 of Salmonella Typhimurium encodes a toxin and a reverse transcriptase, which, together with the Sen2 multi-copy single-stranded DNA synthesized by the reverse transcriptase make up a tripartite toxin–antitoxin system that functions in anti-phage defence.

    • Jacob Bobonis
    • Karin Mitosch
    • Athanasios Typas
    Research
    Nature
    Volume: 609, P: 144-150

  • Salmonella Typhimurium replicates within host phagocytes. Here, the authors show that a known psychoactive drug (metergoline) inhibits growth of the pathogen in macrophages, disrupts the proton motive force at the bacterial cytoplasmic membrane, and extends animal survival during systemic infection.

    • Michael J. Ellis
    • Caressa N. Tsai
    • Eric D. Brown
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14