Nature Search

A direct comparison of natural and acoustic-radiation-force-induced cardiac mechanical waves

Lana B. H. Keijzer
Annette Caenen
Hendrik J. Vos
ResearchOpen Access28 Oct 2020
Scientific Reports

Volume: 10, P: 1-15
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

Selective inhibitors of KAT6A and KAT6B inhibit MYST-catalysed histone acetylation, induce cell cycle exit and cellular senescence without causing DNA damage, and arrest lymphoma progression in mouse models.

Jonathan B. Baell
David J. Leaver
Tim Thomas
Research01 Aug 2018
Nature

Volume: 560, P: 253-257
ELMO2 is an essential regulator of carotid artery development

Here they show that ELMO2 is crucial for vascular development, with knockout mice being nonviable due to carotid artery aneurysms. ELMO2 regulates vascular smooth muscle cell behavior, offering insights into VMOS disease and potential treatment strategies.

Athira Suresh
Kai Kruse
Ralf H. Adams
ResearchOpen Access02 Jun 2025
Nature Communications

Volume: 16, P: 1-20
Essential role of stromally induced hedgehog signaling in B-cell malignancies

Christine Dierks
Jovana Grbic
Markus Warmuth
Research15 Jul 2007
Nature Medicine

Volume: 13, P: 944-951
MADS1 maintains barley spike morphology at high ambient temperatures

In barley, a MADS transcription factor regulates inflorescence morphogenesis in response to warm temperature. MADS1 maintains unbranched spike morphology through repression of cell division in the spike meristem. A loss-of-function mutant forms branch-like spikes.

Gang Li
Hendrik N. J. Kuijer
Dabing Zhang
Research28 Jun 2021
Nature Plants

Volume: 7, P: 1093-1107
SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion

Sustained Wnt secretion requires the endosomal SNX3-retromer complex for endosome-to-trans-Golgi network transport of the internalised Wnt chaperone Wntless. Here the authors show that in both C. elegans and human cells, SNX3-retromer requires an evolutionary conserved membrane remodelling complex for Wntless sorting and Wnt secretion.

Ian J. McGough
Reinoud E. A. de Groot
Peter J. Cullen
ResearchOpen Access13 Sept 2018
Nature Communications

Volume: 9, P: 1-13
Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes

Pericytes are perivascular cells essential for blood-brain barrier maintenance. Here Diéguez-Hurtado et al. show that depletion of the transcription factor RBPJ in pericytes affects their molecular identity and disturbs endothelial cell behaviour, inducing the formation of vascular lesions in the brain.

Rodrigo Diéguez-Hurtado
Katsuhiro Kato
Ralf H. Adams
ResearchOpen Access27 Jun 2019
Nature Communications

Volume: 10, P: 1-19
Two-stage visual speech recognition for intensive care patients

Hendrik Laux
Ahmed Hallawa
Arne Peine
ResearchOpen Access17 Jan 2023
Scientific Reports

Volume: 13, P: 1-10
Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1

Pericytes are essential for the development, maintenance and function of vascular networks. Here, Eilken and colleagues show that expression of the decoy receptor VEGFR1 by pericytes spatially restricts VEGF signalling, thus regulating VEGF-induced endothelial cell sprouting in developing tissues.

Hanna M. Eilken
Rodrigo Diéguez-Hurtado
Ralf H. Adams
ResearchOpen Access17 Nov 2017
Nature Communications

Volume: 8, P: 1-14
The life cycle of non-polio enteroviruses and how to target it

In recent years, several non-polio enteroviruses (NPEVs) have emerged as serious public health concerns. In this Review, van Kuppeveld and colleagues summarize recent insights from enterovirus research, with a special emphasis on NPEVs, and reflect on how recent discoveries may help in the development of new antiviral strategies.

Jim Baggen
Hendrik Jan Thibaut
Frank J. M. van Kuppeveld
Reviews06 Apr 2018
Nature Reviews Microbiology

Volume: 16, P: 368-381

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